P4.17 ARTERIAL STIFFNESS IN YOUNG PATIENTS WITH PERIPHERAL ARTERIAL DISEASE

DOI

10.1016/j.artres.2015.10.261How to use a DOI?

Abstract

Increased arterial stiffness occurs in older patients with peripheral arterial disease (PAD). In this study we compared arterial stiffness and central hemodynamic parameters in young (< 60 years of age) PAD patients and controls. In 31 PAD patients with an ankle-brachial index (ABI≤ 0.9) and 42 controls, aortic Pulse wave velocity (aPWV), Augmentation index corrected for heart rate (AIx@75HR), aortic Pulse Pressure (aPP), Pulse Pressure Amplification (PPA), were measured using the SphygmoCor device. In young PAD patients aPWV and AIx@75HR were similar (p=0.10) (p=0.58) With respect to controls but aortic PP was higher (p=0.02) and the PP amplification ratio was lower (p=0.005). PAD in young subjects is associated with central hemodynamic alterations but not with degenerative stiffness of the large arteries.

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TY  - JOUR
AU  - Mariella Catalano*
AU  - Giovanni Scandale
AU  - Gabriel Dimitrov
AU  - Marzio Minola
AU  - Martino Recchia
AU  - Francesca Galli
AU  - Gianni Carzaniga
AU  - Maria Carotta
PY  - 2015
DA  - 2015/11/23
TI  - P4.17 ARTERIAL STIFFNESS IN YOUNG PATIENTS WITH PERIPHERAL ARTERIAL DISEASE
JO  - Artery Research
SP  - 19
EP  - 19
VL  - 12
IS  - C
SN  - 1876-4401
UR  - https://doi.org/10.1016/j.artres.2015.10.261
DO  - 10.1016/j.artres.2015.10.261
ID  - Catalano*2015
ER  -