P3.1 SUB-MAXIMAL EXERCISE BLOOD PRESSURE RELATES TO LEFT VENTRICULAR MASS INDEX, BUT IS DEPENDENT ON LOW AEROBIC CAPACITY

Martin Schultz*; Dean Picone; Rachel Climie; Costan Magnussen; Leah Wright; Thomas Marwick; Alison Venn; James Sharman

doi:10.1016/j.artres.2015.10.226

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Volume 12, Issue C, December 2015, Pages 10 - 11

P3.1 SUB-MAXIMAL EXERCISE BLOOD PRESSURE RELATES TO LEFT VENTRICULAR MASS INDEX, BUT IS DEPENDENT ON LOW AEROBIC CAPACITY

Authors

Martin Schultz*¹, Dean Picone¹, Rachel Climie¹, Costan Magnussen¹^{, 2}, Leah Wright¹, Thomas Marwick¹, Alison Venn¹, James Sharman¹

¹Menzies Institute for Medical Research, University of Tasmania, Hobart, Australia

²Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, Turku, Finland

Available Online 23 November 2015.

DOI: 10.1016/j.artres.2015.10.226 How to use a DOI?
Abstract: Background: Exaggerated blood pressure (BP) responses to sub-maximal exercise independently predict cardiovascular (CV) events, mortality and incident hypertension. The aim of this study was to explore relationships between exercise BP, left-ventricular (LV) structure and function and aerobic fitness as potential mechanisms underlying the CV risk associated with sub-maximal exercise BP.

Methods: 149 participants aged 40±2 years, 45% male completed a staged cycle test to estimate physical work capacity (aerobic fitness; PWC170) with concomitant BP measured each two minutes. 2D echocardiography was used to quantify LV mass (obtained from 2D-guided M-mode echo), and LV function (longitudinal strain, haemodynamics).

Results: Early-stage exercise systolic BP was associated with aerobic fitness and LV mass index (r=0.22, and 0.24, p<0.05) and was greater in those performing high stage-relative work (high-fitness) compared with low stage-relative work (low-fitness) (154±22 vs. 133±15 mmHg, p<0.001). The high-fitness group had greater stroke volume, lower heart rate and LV longitudinal strain compared to the low-fitness group (72±18 vs. 59±15 ml, 61±9 vs. 68±9 bpm, −18±4 vs. −20±3%, p<0.05 for all). Exercise systolic BP was associated with LV mass index independent of resting BP, age and sex in the low-fitness group during stage one of the PWC170 (β=0.13, 95% CI=0.01-0.3) but not in the high-fitness group at any stage.

Conclusions: Sub-maximal exercise systolic BP independently relates to LV mass index in those with low, early stage-relative aerobic capacity. BP measured during submaximal exercise testing (light-intensity) may reveal early changes in hypertension-related organ damage that are more evident in people with low-fitness.
Open Access: This is an open access article distributed under the CC BY-NC license.

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Journal: Artery Research
Volume-Issue: 12 - C
Pages: 10 - 11
Publication Date: 2015/11/23
ISSN (Online): 1876-4401
ISSN (Print): 1872-9312
DOI: 10.1016/j.artres.2015.10.226 How to use a DOI?
Open Access: This is an open access article distributed under the CC BY-NC license.

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ris enw bib

TY  - JOUR
AU  - Martin Schultz*
AU  - Dean Picone
AU  - Rachel Climie
AU  - Costan Magnussen
AU  - Leah Wright
AU  - Thomas Marwick
AU  - Alison Venn
AU  - James Sharman
PY  - 2015
DA  - 2015/11/23
TI  - P3.1 SUB-MAXIMAL EXERCISE BLOOD PRESSURE RELATES TO LEFT VENTRICULAR MASS INDEX, BUT IS DEPENDENT ON LOW AEROBIC CAPACITY
JO  - Artery Research
SP  - 10
EP  - 11
VL  - 12
IS  - C
SN  - 1876-4401
UR  - https://doi.org/10.1016/j.artres.2015.10.226
DO  - 10.1016/j.artres.2015.10.226
ID  - Schultz*2015
ER  -

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