P2.7 AMELIORATION OF COGNITIVE FUNCTION IN HEMODIALYSIS PATIENTS IN ABSENT OF HYPOTENSIVES EPISODES

Despina Karasavvidou*; Eleni Triantafilidou; Dimitrios Valoukas; Dimitrios Makridis; Sygliti-Errieta Pelidou; Cristos katsinas

doi:10.1016/j.artres.2015.10.214

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Volume 12, Issue C, December 2015, Pages 7 - 8

P2.7 AMELIORATION OF COGNITIVE FUNCTION IN HEMODIALYSIS PATIENTS IN ABSENT OF HYPOTENSIVES EPISODES

Authors

Despina Karasavvidou*¹, Eleni Triantafilidou¹, Dimitrios Valoukas¹, Dimitrios Makridis¹, Sygliti-Errieta Pelidou², Cristos katsinas¹

¹Department of Nephrology, General Hospital of Ptolemaida, Ptolemaida, Greece

²Department of Neurology, University of Ioannina, Ioannina, Greece

Available Online 23 November 2015.

DOI: 10.1016/j.artres.2015.10.214 How to use a DOI?
Abstract: Objective: Patients in hemodialysis frequently have cognitive dysfunction (CO/DY). Hemodialysis session often results in acute intravascular volume loss, fluid shifts, hypotensives episodes, decrease of cerebral perfusion and cerebral ischemia, all of which may cause transient deterioration of cognitive function. On the contrary, improvement in “uremic milieu” after a dialysis session can result in improved cognition. The aim of this study is to evaluate the effect of a single, random hemodialysis session on cognitive function, in absent of hypotensive episodes.

Method: Global cognitive function was assessed, pre-and post-dialysis by using the Mini Mental State Examination.

Results: Forty-eight patients participated in the study. The average age was 60.8±13.4 years. The mean dialysis vintage was 58±66 months. Patients received adequate renal replacement therapy and the mean urea reduction ratio was 72±6.6. At the onset and at the end of the study, no major hemodynamic changes were detecting (mean systolic/diastolic blood pressure (147.±20/78±11 vs 138±20/77±10 mmHg) according to our aforementioned criteria. Compared to pre- dialysis, an improvement in the test score was revealed after dialysis, paired t-test (p=0.03). Mean values of MMSE pre and post was 26.61 ± 3.24 and 28.86± 1.98 respectively (amelioration of 2.25 points).

Conclusions: Our results illustrate the better performance of cognitive function that can be observed after a single dialysis session, in absent of hypotensives episodes. These results may be used as a starting point, in an effort to evaluate the best possible time, pre or post dialysis, to provide medical advice to these patients.
Open Access: This is an open access article distributed under the CC BY-NC license.

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Journal: Artery Research
Volume-Issue: 12 - C
Pages: 7 - 8
Publication Date: 2015/11/23
ISSN (Online): 1876-4401
ISSN (Print): 1872-9312
DOI: 10.1016/j.artres.2015.10.214 How to use a DOI?
Open Access: This is an open access article distributed under the CC BY-NC license.

Cite this article

ris enw bib

TY  - JOUR
AU  - Despina Karasavvidou*
AU  - Eleni Triantafilidou
AU  - Dimitrios Valoukas
AU  - Dimitrios Makridis
AU  - Sygliti-Errieta Pelidou
AU  - Cristos katsinas
PY  - 2015
DA  - 2015/11/23
TI  - P2.7 AMELIORATION OF COGNITIVE FUNCTION IN HEMODIALYSIS PATIENTS IN ABSENT OF HYPOTENSIVES EPISODES
JO  - Artery Research
SP  - 7
EP  - 8
VL  - 12
IS  - C
SN  - 1876-4401
UR  - https://doi.org/10.1016/j.artres.2015.10.214
DO  - 10.1016/j.artres.2015.10.214
ID  - Karasavvidou*2015
ER  -

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