P2.5 SEX-DEPENDENT DIFFERENCES IN OBESITY INDICES AND INFLAMMATORY MARKERS IN NON-DIABETIC OBESE PATIENTS

DOI

10.1016/j.artres.2015.10.212How to use a DOI?

Abstract

Background: The aim of the study was to asses sex-dependent differences of obesity indices and inflammatory markers in non-diabetic hypertensive obese patients.

Material and methods: 40 females and 25 males aged 59.8 ±10.1 and 54.6±11.9 years, respectively, were enrolled into the study. Serum TNF-α, IL-6 and high-sensitivity C-reactive protein (hs-CRP) levels were estimated. Waist circumference (WC), waist-to-hip ratio (WHR), body mass index (BMI), waist-to-height ratio (WHtR), visceral adiposity index (VAI) and body adiposity index (BAI) were measured or calculated.

Results: In males WC and WHR were higher than in females (117.0 ±10.8 cm vs 108.5 ±10.4 cm; p < 0.01 and 1.01±0.06 vs 0.91±0.06; p < 0.0001, respectively). In females BAI and hs-CRP were higher than in the males (41.7 ±6.9 vs 33.5 ±5.0; p < 0.0001 and 3.2 ±2.2 mg/l vs 2.1 ±1.5 mg/l; p < 0.05, respectively).

In females hs-CRP positively correlated with WHtR (r = 0.321; p< 0.05), BMI and BAI (r = 0.305; p = 0.05, and r = 0.309; p = 0.05, respectively). In males hs-CRP positively correlated with WHtR, BAI and VAI (r= 0.458; p < 0.05; r = 0.440; p < 0.05 and r = 0.443; p < 0.05, respectively), IL-6 positively correlated with VAI (r = 0.472; p < 0.05) and TNF-α negatively correlated with WHR (r = −0.408; p < 0.05).

Conclusions: Obesity related chronic inflammation is more evident in females than in males. Differences in WC, WHR and BAI are sex dependent.

Open Access

This is an open access article distributed under the CC BY-NC license.

TY  - JOUR
AU  - Mariusz Stępień*
AU  - Anna Stępień
AU  - Rafał N. Wlazeł
AU  - Marek Paradowski
AU  - Maciej Banach
AU  - Jacek Rysz
PY  - 2015
DA  - 2015/11/23
TI  - P2.5 SEX-DEPENDENT DIFFERENCES IN OBESITY INDICES AND INFLAMMATORY MARKERS IN NON-DIABETIC OBESE PATIENTS
JO  - Artery Research
SP  - 7
EP  - 7
VL  - 12
IS  - C
SN  - 1876-4401
UR  - https://doi.org/10.1016/j.artres.2015.10.212
DO  - 10.1016/j.artres.2015.10.212
ID  - Stępień*2015
ER  -