Artery Research

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Volume 20, Issue C, December 2017, Pages 88 - 88

P93 ARE HEMODYNAMIC MEASURES ASSOCIATED WITH FRAILTY IN ELDERLY PATIENTS UNDERGOING TRANSCATHETER AORTIC VALVE IMPLANTATION?

Authors
Jeannette Goudzwaard1, Marjo de Ronde-Tillmans2, Nahid El Faquir2, Nicolas van Mieghem2, Mattie Lenzen2, Peter de Jaegere2, Francesco Mattace Raso1
1Section of Geriatrics, Department of Internal Medicine, Erasmus University Medical Center, Netherlands
2Department of Interventional Cardiology, Thorax Center, Erasmus University Medical Center, Netherlands
Available Online 6 December 2017.
DOI
10.1016/j.artres.2017.10.130How to use a DOI?
Abstract

Background: Aortic valve stenosis (AS) is common in the elderly and is associated with high morbidity and mortality, and leads to functional decline. The aim of this study was to investigate the possible relation between aortic stiffness, AS and frailty in older patients undergoing Transcatheter Aortic Valve Implantation (TAVI).

Methods: TAVI Care&Cure is an observational ongoing study including consecutive patients undergoing TAVI procedure at the Erasmus University Medical Center. Prior to TAVI echocardiography was performed and aortic stiffness was measured non-invasively by the Mobil-O-Graph. The frailty status was assessed including 5 domains. Primary outcome was to investigate the relationship between structural and functional cardiovascular parameters and frailty status. Linear regression was used.

Results: A total of 212 patients were included for analysis. Mean age was 79,2 years (±7,8), 52,7% men, mean Aortic Valve Area (AVA) was 0,73 (± 0,3), mean Pulse Wave Velocity was 12,6 (±1,5). Frailty was found in 57,8%. Peripheral pulse pressure (p = 0.04) and central pulse pressure (p = 0.02) but not aortic stiffness were associated with AS severity. AVA was associated with frailty (p = 0.02) whereas measures of aortic stiffness were not.

Conclusion: Aortic valve area but not measures of aortic stiffness is associated with frailty status in elderly patients with AS undergoing a TAVI procedure.

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<Previous Article In Issue
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Journal
Artery Research
Volume-Issue
20 - C
Pages
88 - 88
Publication Date
2017/12/06
ISSN (Online)
1876-4401
ISSN (Print)
1872-9312
DOI
10.1016/j.artres.2017.10.130How to use a DOI?
Open Access
This is an open access article distributed under the CC BY-NC license.

Cite this article

risenwbib
TY  - JOUR
AU  - Jeannette Goudzwaard
AU  - Marjo de Ronde-Tillmans
AU  - Nahid El Faquir
AU  - Nicolas van Mieghem
AU  - Mattie Lenzen
AU  - Peter de Jaegere
AU  - Francesco Mattace Raso
PY  - 2017
DA  - 2017/12/06
TI  - P93 ARE HEMODYNAMIC MEASURES ASSOCIATED WITH FRAILTY IN ELDERLY PATIENTS UNDERGOING TRANSCATHETER AORTIC VALVE IMPLANTATION?
JO  - Artery Research
SP  - 88
EP  - 88
VL  - 20
IS  - C
SN  - 1876-4401
UR  - https://doi.org/10.1016/j.artres.2017.10.130
DO  - 10.1016/j.artres.2017.10.130
ID  - Goudzwaard2017
ER  -