Artery Research

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Volume 20, Issue C, December 2017, Pages 65 - 66

P37 REFERENCE VALUES OF CARDIO-ANKLE VASCULAR INDEX IN A RANDOM SAMPLE OF A CAUCASIAN POPULATION

Authors
Peter Wohlfahrt1, 2, 3, Renata Cífková4, 2, Narine Movsisyan1, Šárka Kunzová1, Jiří Lešovský1, Martin Homolka1, 5, 6, Vladimír Soška1, Petr Dobšák1, Francisco Lopez- Jimenez7, Ondřej Sochor7, 8
1International Clinical Research Center, St. Anne’s University Hospital, Czech Republic
2Center for Cardiovascular Prevention of the First Faculty of Medicine, Charles University and Thomayer Hospital, Czech Republic
3Laboratory for Atherosclerosis Research, Institute for Clinical and Experimental Medicine, Czech Republic
4International Clinical Research Center, Czech Republic
52nd Clinic of Internal Medicine, Department of Laboratory Methods, Masaryk University, Czech Republic
6Department of Clinical Biochemistry, St. Anne’s University Hospital of Brno, Czech Republic
7Division of Cardiovascular Diseases, Mayo Clinic, Rochester, MN, USA
8International Clinical Research Center, St. Anne’s University Hospital, Brno, Czech Republic
Available Online 6 December 2017.
DOI
10.1016/j.artres.2017.10.067How to use a DOI?
Abstract

Objectives: Cardio-ankle vascular index (CAVI), a parameter of arterial stiffness, has been increasingly used for cardiovascular risk estimation. Currently used CAVI reference values are derived from the Japanese population. It is not clear whether the same reference values can be used in the Caucasian population. The aim of the present study was to describe cardiovascular risk factors influencing CAVI and to establish CAVI reference values.

Methods: 2160 individuals randomly selected from the Brno city population aged 25–65 years were examined. Of these, 1347 subjects were free from cardiovascular disease, non- diabetic and untreated by antihypertensive or lipid-lowering drugs, forming the reference value population. CAVI was measured using the VaSera VS-1000 device.

Results: At each blood pressure (BP) level, there was a quadratic association between CAVI and age, except for a linear association in the optimal BP group. While there was no association between BP and CAVI in younger subjects, there was a linear association between CAVI and BP after 40 years of age. Reference values by age and gender were established. In each age group, except for the male 60–65 group, reference values in our population were lower than in the Japanese one with the difference ranging from −0.29 to 0.21 for males, and from −0.38 to −0.03 for females.

Conclusion: This is the first study providing CAVI reference values in a random sample of the Caucasian population. Our results suggest that the currently used values slightly overestimate CAVI in younger Caucasian, possibly underestimating cardiovascular risk.

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This is an open access article distributed under the CC BY-NC license.

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Journal
Artery Research
Volume-Issue
20 - C
Pages
65 - 66
Publication Date
2017/12/06
ISSN (Online)
1876-4401
ISSN (Print)
1872-9312
DOI
10.1016/j.artres.2017.10.067How to use a DOI?
Open Access
This is an open access article distributed under the CC BY-NC license.

Cite this article

risenwbib
TY  - JOUR
AU  - Peter Wohlfahrt
AU  - Renata Cífková
AU  - Narine Movsisyan
AU  - Šárka Kunzová
AU  - Jiří Lešovský
AU  - Martin Homolka
AU  - Vladimír Soška
AU  - Petr Dobšák
AU  - Francisco Lopez- Jimenez
AU  - Ondřej Sochor
PY  - 2017
DA  - 2017/12/06
TI  - P37 REFERENCE VALUES OF CARDIO-ANKLE VASCULAR INDEX IN A RANDOM SAMPLE OF A CAUCASIAN POPULATION
JO  - Artery Research
SP  - 65
EP  - 66
VL  - 20
IS  - C
SN  - 1876-4401
UR  - https://doi.org/10.1016/j.artres.2017.10.067
DO  - 10.1016/j.artres.2017.10.067
ID  - Wohlfahrt2017
ER  -