Artery Research

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Volume 24, Issue C, December 2018, Pages 126 - 126

P159 CORRELATION BETWEEN INFLAMMATORY STATE AND ARTERIAL STIFFNESS

Authors
Daniele Brustolim1, Lucelia Magalhaes2, Diorlene Silva2, Rodrigo Sant’Ana de Lima2, Vinicius Louzada Castro3, Daniel Malta Ribeiro4, Caroline Rodrigues Fidelman4, Natalia Damasceno4, Larissa Vasconcelos4, Caroline Ventura2, Vascor Group2
1FTC medicina, Brazil
2Medical School, University Center of Science andTecnology (FTC), Salvador, Brazil
3Federal Univerty of Bahia (UFBA), Salvador, Brazil
4School of Medicine and Health Bahiana, Salvador, Brazil
Available Online 4 December 2018.
DOI
10.1016/j.artres.2018.10.212How to use a DOI?
Abstract

Pulse wave velocity (PWV) is gold standard for assessing arterial stiffness. Studies have shown that people with metabolic syndrome have insulin resistance and that after the onset of diabetes, cardiovascular risk is intensely increased, high-sensitive C-reactive protein (hsCRP) (1). Relate influence of changes in pulse wave velocity in the severity of the inflammatory state (2).

Methods: A population-based cross-sectional study representative of a neighborhood of Salvador-BA, Brazil. The overall sample is randomized in adults from the assigned area, from December 2016 to May 2018 comprise 64 people. PWV was the measuring velocity between the carotid and right femoral wave. The flattening tonometer SphygmoCor® apparatus (XCEL, AtCor Medical, Australia). Blood samples were collected to biochemistry analysis, ADVIA1800® (SiemensHealthcare Japan/Canada). The committee for research FTC protocol (No1827621). Spearman’s linear correlation coefficient between the laboratory tests and adjusted PWV were stratified according to the increased risk level of adjusted PWV. STATA v.12 for data analysis. The level of statistical significance was set at 5%.

Results: Table 1 (image 1), predominance of women (72.3%), (n = 64). When compared to the group with normal pulse wave velocity, there was an increase in the parameters of the laboratory tests in the group with an increased risk of arterial stiffness (adjusted PWV ≥ 10), the correlations in this group and the PWV were positive and weak, except for the glycemia was negative, but they were not statistically significant. Already in the group with normal PWV, the correlations were positive and weak, only triglycerides presented.

Conclusion: New molecular markers is necessary for correlate low intensity inflammation and arterial stiffness.

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This is an open access article distributed under the CC BY-NC license.

References

1.Ioana Mozos et al., Inflammatory Markers for Arterial Stiffness in Cardiovascular Diseases, Frontiers in Immunology, Vol. 8, 2017, pp. 1058.
2.B Bozkurt, D Mann, and A Deswal, Biomarkers of inflammation in heart failure, Heart Fail Rev, Vol. 15, 2010, pp. 331-341.
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Journal
Artery Research
Volume-Issue
24 - C
Pages
126 - 126
Publication Date
2018/12/04
ISSN (Online)
1876-4401
ISSN (Print)
1872-9312
DOI
10.1016/j.artres.2018.10.212How to use a DOI?
Open Access
This is an open access article distributed under the CC BY-NC license.

Cite this article

risenwbib
TY  - JOUR
AU  - Daniele Brustolim
AU  - Lucelia Magalhaes
AU  - Diorlene Silva
AU  - Rodrigo Sant’Ana de Lima
AU  - Vinicius Louzada Castro
AU  - Daniel Malta Ribeiro
AU  - Caroline Rodrigues Fidelman
AU  - Natalia Damasceno
AU  - Larissa Vasconcelos
AU  - Caroline Ventura
AU  - Vascor Group
PY  - 2018
DA  - 2018/12/04
TI  - P159 CORRELATION BETWEEN INFLAMMATORY STATE AND ARTERIAL STIFFNESS
JO  - Artery Research
SP  - 126
EP  - 126
VL  - 24
IS  - C
SN  - 1876-4401
UR  - https://doi.org/10.1016/j.artres.2018.10.212
DO  - 10.1016/j.artres.2018.10.212
ID  - Brustolim2018
ER  -