Artery Research

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Volume 24, Issue C, December 2018, Pages 100 - 101

P76 CAROTID THERMAL HETEROGENEITY AND DYSLIPIDEMIA: THE HEAT IS ON

Authors
Iosif Koutagiar, Charalambos Vlachopoulos, Dimitrios Terentes-Printzios, Ioannis Skoumas, Evangelia Sigala, Vasiliki Gardikioti, Stavroula Pantou, Angeliki Rigatou, Nikolaos Ioakeimidis, Christos Georgakopoulos, Nikitas-Alexandros Skliros, Georgios Benetos, Spiros Galanakos, Dimitrios Tousoulis
Hippokrateion Hospital, Medical School University of Athens, Athens, Greece
Available Online 4 December 2018.
DOI
10.1016/j.artres.2018.10.129How to use a DOI?
Abstract

Background: Microwave Radiometry (MWR) is a new validated method, which allows evaluation of thermal heterogeneity of carotid arteries and is associated with inflammation.Purpose: The aim of this pilot study was to determine if thermal heterogeneity in the carotid arteries is associated with aortic elastic properties in patients with dyslipidemia and whether treatment for dyslipidemia affects thermal heterogeneity.

Method: Twenty-nine patients with dyslipidemia (mean age 42 ± 13 years, range 22–75, 19 men) without known cardiovascular disease, underwent assessment of carotid thermal heterogeneity (temperature difference-ΔT) using MWR. Mean common carotid intima-media thickness (CIMT) was also assessed. Twenty-one patients were treated for 6 months with statin or/and ezetimibe and thermal heterogeneity was assessed after treatment.

Results: There was a positive correlation between ΔT and cIMT (r = 0.474, p = 0.009). In multivariate regression analysis, after adjustment for potential confounders such as age, sex, mean blood pressure and body-mass index, cIMT showed a positive correlation with ΔT in carotid arteries (Adjusted R2 = 0.258, p = 0.048). Thermal heterogeneity after 6 months of treatment was reduced statistically significant (0.88 ± 0.42 to 0.58 ± 0.29 °C, p = 0.021) (Image).

Conclusion: In a group of patients with dyslipidemia thermal heterogeneity in the carotid arteries was positively associated with carotid subclinical atherosclerosis. Moreover, dyslipidemia treatment reduced thermal heterogeneity after a short-term period, implying a beneficial effect of treatment on thermal heterogeneity.

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This is an open access article distributed under the CC BY-NC license.

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Journal
Artery Research
Volume-Issue
24 - C
Pages
100 - 101
Publication Date
2018/12/04
ISSN (Online)
1876-4401
ISSN (Print)
1872-9312
DOI
10.1016/j.artres.2018.10.129How to use a DOI?
Open Access
This is an open access article distributed under the CC BY-NC license.

Cite this article

risenwbib
TY  - JOUR
AU  - Iosif Koutagiar
AU  - Charalambos Vlachopoulos
AU  - Dimitrios Terentes-Printzios
AU  - Ioannis Skoumas
AU  - Evangelia Sigala
AU  - Vasiliki Gardikioti
AU  - Stavroula Pantou
AU  - Angeliki Rigatou
AU  - Nikolaos Ioakeimidis
AU  - Christos Georgakopoulos
AU  - Nikitas-Alexandros Skliros
AU  - Georgios Benetos
AU  - Spiros Galanakos
AU  - Dimitrios Tousoulis
PY  - 2018
DA  - 2018/12/04
TI  - P76 CAROTID THERMAL HETEROGENEITY AND DYSLIPIDEMIA: THE HEAT IS ON
JO  - Artery Research
SP  - 100
EP  - 101
VL  - 24
IS  - C
SN  - 1876-4401
UR  - https://doi.org/10.1016/j.artres.2018.10.129
DO  - 10.1016/j.artres.2018.10.129
ID  - Koutagiar2018
ER  -