Artery Research

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Volume 24, Issue C, December 2018, Pages 98 - 99

P70 FINGER-TOE PULSE WAVE VELOCITY (FTPWV) MEASURED BY POPMèTRE® DEVICE IN PATIENTS WITH ANKYLOSING SPONDYLITIS

Authors
Guillermo Alanis-Sánchez1, Carlos Ramos-Becerra2, Ernesto Cardona-Muñóz3, Diego Castañeda-Zaragoza3, David Cardona-Muller3, Hakim Khettab4, Stephen Laurent5, Pierre Boutouyrie4, Hasan Obeid4, Magid Hallab6, Valeria Diaz-Rizo3
1West Lab ICORD, University of British Columbia, Canada
2University of Guadalajara, Department of Physiology, Arterial Stiffness, Canada
3Arterial Stiffness Laboratory, Department of Physiology, University of Guadalajara, Mexico
4Inserm U970, France Paris Descartes University and HEGP, Paris, France
5Inserm U970, France (2) Paris Descartes University and HEGP, Paris, France
6Centre Hospitalier Universitaire de Nantes Pôle de Gérontologie Clinique, Nantes, France
Available Online 4 December 2018.
DOI
10.1016/j.artres.2018.10.123How to use a DOI?
Abstract

Background: Ankylosing spondylitis (AS) is an inflammatory autoimmune disease. AS is a prototype form of spondyloarthropathies (SpA). The precise ethology of AS has not been fully understood. But Inflammation has a critical role in the pathogenesis of the disease. Extra skeletal organs may also be affected by this disease and is also associated with an increase of cardiovascular risk. The effect of large arteries appears by a stiffness that can be an element of disease monitoring.

Objective: The objective of this study was to evaluate the finger-toe Pulse Wave Velocity (ftPWV) in patients with AS.

Methods: Finger-toe pulse wave velocity (ft-PWV) was measured by pOpmetre® allowed to explore arterial stiffness.

Results: Demographic and clinical characteristics are presented in Table 1. Twenty-two patients with AS and 24 controls were included in our study, subjects with AS exhibited greater pSBP (p < 0.001), pDBP (p < 0.001), pPP (p < 0.001) and MBP (p < .001) compared to controls. Moreover, in the AS group we observed a higher ftPWV with a mean difference of 1.63 (p < 0.006, 95% CI of .50 to 2.7). No significant difference was observed in pPP.

Conclusions: Individuals with ankylosing spondylitis showed increased ftPWV, central and peripheral blood pressure, this contributes to explain the higher risk of cardiovascular disease in this pathology. pOpmètre® is a no operator depended, simple and practical device, highlighted an increase in arterial stiffness in patients with AS by measuring the ft-PWV. It could play a role in this disease monitoring and in prediction of cardiovascular complications.

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This is an open access article distributed under the CC BY-NC license.

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Journal
Artery Research
Volume-Issue
24 - C
Pages
98 - 99
Publication Date
2018/12/04
ISSN (Online)
1876-4401
ISSN (Print)
1872-9312
DOI
10.1016/j.artres.2018.10.123How to use a DOI?
Open Access
This is an open access article distributed under the CC BY-NC license.

Cite this article

risenwbib
TY  - JOUR
AU  - Guillermo Alanis-Sánchez
AU  - Carlos Ramos-Becerra
AU  - Ernesto Cardona-Muñóz
AU  - Diego Castañeda-Zaragoza
AU  - David Cardona-Muller
AU  - Hakim Khettab
AU  - Stephen Laurent
AU  - Pierre Boutouyrie
AU  - Hasan Obeid
AU  - Magid Hallab
AU  - Valeria Diaz-Rizo
PY  - 2018
DA  - 2018/12/04
TI  - P70 FINGER-TOE PULSE WAVE VELOCITY (FTPWV) MEASURED BY POPMèTRE® DEVICE IN PATIENTS WITH ANKYLOSING SPONDYLITIS
JO  - Artery Research
SP  - 98
EP  - 99
VL  - 24
IS  - C
SN  - 1876-4401
UR  - https://doi.org/10.1016/j.artres.2018.10.123
DO  - 10.1016/j.artres.2018.10.123
ID  - Alanis-Sánchez2018
ER  -