Artery Research

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Volume 24, Issue C, December 2018, Pages 96 - 96

P60 INFLUENCE OF ANGER ON ENDOTHELIAL DYSFUNCTION IN PATIENTS WITH RECENT MYOCARDIAL INFARCTION

Authors
Bruna Eibel1, Alexandre Quadros2, Karine Schmidt3, Carlos Gottschall3, Márcia Moura3
1Instituto de Cardiologia/Fundação Universitária de Cardiologia, (ARDI Group), Porto Alegre, RS, Brazil
2IC, Brazil
3Instituto de Cardiologia/Fundação Universitária de Cardiologia, Porto Alegre, RS, Brazil
Available Online 4 December 2018.
DOI
10.1016/j.artres.2018.10.113How to use a DOI?
Abstract

Background: The literature demonstrates that anger is associated with cardiovascular disease, but the underlying physiological mechanisms remain undefined. Endothelial dysfunction, present in atherosclerosis, has also been associated with anger.

Purpose: To examine the association between anger and endothelial function measured by flow-mediated dilatation (FMD) of the brachial artery.

Methods: Patients were assessed during hospitalization after acute myocardial infarction answered the Spielberger Trait-State Anger inventory (STAXI). After discharge, patients were submitted to ultrasound of the brachial artery, the FMD technique, which was calculated by the maximum percentual of change in the diameter of the brachial artery from baseline to peak of dilation after deflation of the cuff.

Results: The study included 90 patients, 86% caucasian, with 57 ± 10 years old, 73% male, 48% smokers, 57% with hypertension, 32% with dyslipidemia, 23% with diabetes, and 21% with a family history of arterial disease coronary artery disease. The mean dilation of this group was 6.70 ± 4.64. The presence of endothelial dysfunction was evaluated by the percentage of arterial dilation below 8.0%. In the multivariate analysis, only the anger reaction was associated with endothelial dysfunction. At each point of anger reaction increases 31% the chance of endothelial dysfunction (p = 0.008).

Conclusions: In this sample of infarcted patients with anger score below average, the anger reaction is related to endothelial dysfunction.

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<Previous Article In Issue
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Journal
Artery Research
Volume-Issue
24 - C
Pages
96 - 96
Publication Date
2018/12/04
ISSN (Online)
1876-4401
ISSN (Print)
1872-9312
DOI
10.1016/j.artres.2018.10.113How to use a DOI?
Open Access
This is an open access article distributed under the CC BY-NC license.

Cite this article

risenwbib
TY  - JOUR
AU  - Bruna Eibel
AU  - Alexandre Quadros
AU  - Karine Schmidt
AU  - Carlos Gottschall
AU  - Márcia Moura
PY  - 2018
DA  - 2018/12/04
TI  - P60 INFLUENCE OF ANGER ON ENDOTHELIAL DYSFUNCTION IN PATIENTS WITH RECENT MYOCARDIAL INFARCTION
JO  - Artery Research
SP  - 96
EP  - 96
VL  - 24
IS  - C
SN  - 1876-4401
UR  - https://doi.org/10.1016/j.artres.2018.10.113
DO  - 10.1016/j.artres.2018.10.113
ID  - Eibel2018
ER  -