P16 PULSE WAVE VELOCITY AND ITS ASSOCIATION WITH FIRST CARDIOVASCULAR EVENTS IN A PORTUGUESE HYPERTENSIVE SAMPLE

Clarinda Neves; Joana Ricardo Pires; Verónica Ribau; José Mesquita Bastos

doi:10.1016/j.artres.2018.10.069

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Volume 24, Issue C, December 2018, Pages 84 - 84

P16 PULSE WAVE VELOCITY AND ITS ASSOCIATION WITH FIRST CARDIOVASCULAR EVENTS IN A PORTUGUESE HYPERTENSIVE SAMPLE

Authors

Clarinda Neves¹^{, 2}^{, 3}, Joana Ricardo Pires⁴, Verónica Ribau⁴, José Mesquita Bastos⁴^{, 5}^{, 6}

¹Clarinda Neves, Portugal

²Centro Hospitalar Baixo Vouga, Aveiro, Portugal

³Departamento de Ciências Médicas, Universidade de Aveiro, Portugal

⁴Centro Hospitalar do Baixo Vouga, Aveiro, Portugal

⁵ESSUA, Universidade de Aveiro, Portugal

⁶CINTESIS, Portugal

Available Online 4 December 2018.

DOI: 10.1016/j.artres.2018.10.069 How to use a DOI?
Abstract: Objective: Pulse Wave Velocity (PWV) is considered a marker of cardiovascular (CV) risk prognosis. The objective was to evaluate the association of PWV, other features and CV events in a sample of hypertensive patients.

Design and method: We studied 314 hypertensive patients without previous CV events evaluated by PWV in a Portuguese average-size hospital, through its descriptive and survival analysis.

Results: Of the 314 patients (51% male) ageing 54.0 ± 14.2 years, 31.5% had resistant hypertension, 26.8% were diabetic, 66.6% had hyperlipidaemia, the average body mass index was 28.3 kg m⁻², and 16.6% were active smoker. Through a follow-up of 2.1 ± 2.2 years, 28 patients (8.9%) had a CV event. Comparison of the patients with PWV ≤ 10 ms⁻¹ and the patients with PWV >10 ms−1, showed statistical significance for age (64.3 ± 10.5 vs 50.2 ± 13.4 years, p < 0.0001), casual systolic blood pressure (137.4 ± 16.3 mmHg vs 154.4 ± 21.4 mmHg, p < 0.0001), PWV (7.9 ± 1,2 ms⁻¹ vs 12.2 ± 1.9 ms⁻¹, p < 0.0001) left ventricular hypertrophy (193,3 ± 58.6 vs 235,8 ± 65.1, p < 0.01) and left auricular volume (19,9 ± 3.9 vs 23.3 ± 5.8, p < 0.002). Patients with PWV>10ms⁻¹, 77,3% had left ventricular hypertrophy (p < 0.004) and 70% had left auricular enlargement (p < 0.08). In the survival analysis, the Kaplan Meier curve showed a worse prognosis for CV events with PWV > 10 ms⁻¹ (log rank 6.0, p < 0,014).

Conclusions: Higher PWV indicating worse artery damage is associated with end organ damage like left ventricular hypertrophy and left auricular enlargement. In patients with no previous CV events, PWV>10 ms⁻¹ is an indicator for worse prognosis for CV events.
Open Access: This is an open access article distributed under the CC BY-NC license.

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Journal: Artery Research
Volume-Issue: 24 - C
Pages: 84 - 84
Publication Date: 2018/12/04
ISSN (Online): 1876-4401
ISSN (Print): 1872-9312
DOI: 10.1016/j.artres.2018.10.069 How to use a DOI?
Open Access: This is an open access article distributed under the CC BY-NC license.

Cite this article

ris enw bib

TY  - JOUR
AU  - Clarinda Neves
AU  - Joana Ricardo Pires
AU  - Verónica Ribau
AU  - José Mesquita Bastos
PY  - 2018
DA  - 2018/12/04
TI  - P16 PULSE WAVE VELOCITY AND ITS ASSOCIATION WITH FIRST CARDIOVASCULAR EVENTS IN A PORTUGUESE HYPERTENSIVE SAMPLE
JO  - Artery Research
SP  - 84
EP  - 84
VL  - 24
IS  - C
SN  - 1876-4401
UR  - https://doi.org/10.1016/j.artres.2018.10.069
DO  - 10.1016/j.artres.2018.10.069
ID  - Neves2018
ER  -

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