1.2 ASSOCIATIONS BETWEEN INDICATORS OF CARDIOVASCULAR DISEASE AND PULSE WAVE ANALYSIS AND VELOCITY: A COMPARISON OF DEVICES

Elizabeth Ellins; Lucy Lennon; Olia Papacosta; Goya Wannamethee; Peter Whincup; Julian Halcox

doi:10.1016/j.artres.2018.10.019

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Volume 24, Issue C, December 2018, Pages 67 - 67

1.2 ASSOCIATIONS BETWEEN INDICATORS OF CARDIOVASCULAR DISEASE AND PULSE WAVE ANALYSIS AND VELOCITY: A COMPARISON OF DEVICES

Authors

Elizabeth Ellins¹, Lucy Lennon², Olia Papacosta², Goya Wannamethee², Peter Whincup³, Julian Halcox⁴

¹Swansea Univeristy Medical School, Swansea, UK

²UCL Department of Primary Care & Population Health, UCL, London, UK

³Population Health Research Institute, St George’s University of London,London, UK

⁴Swansea University Medical School, Swansea, UK

Available Online 4 December 2018.

DOI: 10.1016/j.artres.2018.10.019 How to use a DOI?
Abstract: Background: Both the Sphygmocor (S) and Vicorder (V) devices can be used for Pulse Wave Analysis (PWA) and Velocity (PWV). We investigated if there were differences in the associations between markers of Cardiovascular Disease (CVD) and PWA and PWV variables as assessed by the two devices.

Methods: 1,722 men (78.5 ± 4.7 yrs) from the British Regional Heart Study underwent PWA and PWV with the Sphygmocor and Vicorder devices. Carotid artery Intima-media Thickness (cIMT), NT-proBNP and Left Ventricle Hypertrophy (LVH) detected by ECG were also assessed. Multiple regression was used to investigate the associations between cIMT, NT-proBNP and LVH with each of the following measures, central Augmentation Pressure (cAP) Augmentation Index (cAIx) Blood Pressure (cBP) and carotid to femoral PWV.

Results: Men with data obtained from both devices were included (PWA n = 1,373, PWV n = 1,122). Following adjustment for CVD risk factors, Sphygmocor cAP, cAIx and cBP were all positively associated with LVH (p < 0.05), the relationship between Sphygmocor PWV and LVH was negative (OR 0.87 95% CI 0.78–0.97). There were no associations between LVH and Vicorder variables. cAP measured by both devices and cAIx by Vicorder were predictors of NT-proBNP levels (ScAP Beta 0.097 p < 0.05, VcAP Beta 0.153 p < 0.001 & VcAIx Beta 0.129 p < 0.001). Vicorder cBP was the only predictor of cIMT (Beta 0.057 p < 0.05).

Conclusion: The same measures from two devices were predictors of different indicators of CVD. Further exploration is needed to understand these differences, but device used needs to be taken into consideration when comparing findings of these variables with other published results.
Open Access: This is an open access article distributed under the CC BY-NC license.

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Journal: Artery Research
Volume-Issue: 24 - C
Pages: 67 - 67
Publication Date: 2018/12/04
ISSN (Online): 1876-4401
ISSN (Print): 1872-9312
DOI: 10.1016/j.artres.2018.10.019 How to use a DOI?
Open Access: This is an open access article distributed under the CC BY-NC license.

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ris enw bib

TY  - JOUR
AU  - Elizabeth Ellins
AU  - Lucy Lennon
AU  - Olia Papacosta
AU  - Goya Wannamethee
AU  - Peter Whincup
AU  - Julian Halcox
PY  - 2018
DA  - 2018/12/04
TI  - 1.2 ASSOCIATIONS BETWEEN INDICATORS OF CARDIOVASCULAR DISEASE AND PULSE WAVE ANALYSIS AND VELOCITY: A COMPARISON OF DEVICES
JO  - Artery Research
SP  - 67
EP  - 67
VL  - 24
IS  - C
SN  - 1876-4401
UR  - https://doi.org/10.1016/j.artres.2018.10.019
DO  - 10.1016/j.artres.2018.10.019
ID  - Ellins2018
ER  -

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