Artery Research

<Previous Article In Issue
Download article (PDF)
Next Article In Issue>
Volume 1, Issue 2, September 2007, Pages 65 - 65

P.054 RELATIONSHIP BETWEEN, BLOOD VISCOSITY, SHEAR STRESS AND ARTERIAL STIFFNESS IN PATIENTS WITH ARTERIAL HYPERTENSION

Authors
M.W. Rajzer, M. Klocek, W. Wojciechowska, I. Palka, K.L. Kawecka-Jaszcz
Department of Cardiology and Hypertension, Medical College Jagiellonian University, Krakow, Poland
Available Online 30 August 2007.
DOI
10.1016/j.artres.2007.07.111How to use a DOI?
Open Access
This is an open access article distributed under the CC BY-NC license.

The aim of the study was to investigate relationships between whole blood viscosity (WBW), ascending aorta shear stress (AASS) and carotid- femoral pulse wave velocity (PWV) in patients with arterial hypertension (HT).

Material and methods: Study group (G1): 43 pts. with primary HT - (age 53 ± 6.4 yrs.) was compared with control group (G2): 15 normotensives (age − 55 ± 5.9 yrs.) Blood pressure using “Omron M5 I”, PWV using Complior®device, WBV using “Brookfield DV III+pro”, aortic diameter and flow velocity (required for AASS calculation) using VIVID 7 GE ultrasonograph were measured.

Results: SBP (152 ± 11.3 vs 124 ± 9.7 mmHg, p< 0.001), DBP (92 ± 6.1 vs 83 ± 5.2 mmHg, p< 0.001), WBV at shear rate 100–400/ s−1(5.1 ± 1.2 vs 4.3 ± 0.9 cP, p< 0.05) and, PWV (11.8 ± 1.7 vs 8.8 ± 1.6 m/s, p< 0.05) were higher in G1 than in G2 group. Mean AASS was higher (27.7 ± 5.3 vs 21 ± 4.3 dyne/cm2, p< 0.05) in G1 than in G2 group. In G1 group PWV correlated positively with age: (r = 0.37, p< 0.39), SBP: (r = 0.45, p <0.05) and WBV: (r = 0.41, p<0.05), and negatively with AASS: (r = − 0.29, p< 0.05).

Conclusions: Hypertensive patients are characterized by stiffer aorta and higher WBW, as well as lower AASS. Low shear stress seems to be one of the factors responsible for aortic stiffness in hypertensive patients.

<Previous Article In Issue
Download article (PDF)
Next Article In Issue>
Journal
Artery Research
Volume-Issue
1 - 2
Pages
65 - 65
Publication Date
2007/08/30
ISSN (Online)
1876-4401
ISSN (Print)
1872-9312
DOI
10.1016/j.artres.2007.07.111How to use a DOI?
Open Access
This is an open access article distributed under the CC BY-NC license.

Cite this article

risenwbib
TY  - JOUR
AU  - M.W. Rajzer
AU  - M. Klocek
AU  - W. Wojciechowska
AU  - I. Palka
AU  - K.L. Kawecka-Jaszcz
PY  - 2007
DA  - 2007/08/30
TI  - P.054 RELATIONSHIP BETWEEN, BLOOD VISCOSITY, SHEAR STRESS AND ARTERIAL STIFFNESS IN PATIENTS WITH ARTERIAL HYPERTENSION
JO  - Artery Research
SP  - 65
EP  - 65
VL  - 1
IS  - 2
SN  - 1876-4401
UR  - https://doi.org/10.1016/j.artres.2007.07.111
DO  - 10.1016/j.artres.2007.07.111
ID  - Rajzer2007
ER  -