06.02 AORTIC AND CAROTID STIFFNESS IN OLDER ADULTS. THE ROTTERDAM STUDY
- DOI
- 10.1016/j.artres.2007.07.047How to use a DOI?
- Open Access
- This is an open access article distributed under the CC BY-NC license.
The purpose of this study is to describe aortic (aPWV) and carotid stiffness (DC) in older adults according to age, gender and blood pressure. Information on both measures was available for 2766 subjects. The mean value of both aPWV and DC was lower in women than in men. The difference (95% CI) in aPWV was −0.99 (−0.81 to −1.18) (m/s) and the difference in DC was −1.62 (−1.35 to −1.82) (10−3/kPa) for women as compared for men. With aging, both aorta and carotid artery become stiffer but the increase attenuates at high age. Women under 80 years of age had a less stiff aorta and a stiffer common carotid artery as compared to men of the same age. The relations of both measures of arterial stiffness with SBP and PP were non-linear, flattening off at higher levels, whereas the relation with DBP was non-linear and resembled a J-shape. We found a quadratic relationship between DC and aPWV: DC = 27.4 − 1.9 ∗ (aPWV) + 0.04 ∗ (aPWV)2 [p total model ≤ 0.001], (R2= −0.41, P<0.001). Subjects with increased aortic stiffness had a 30-fold increased risk of also having increased carotid stiffness, OR 31.2 (95% CI 20.9−46.4) (Figure 1).
Cite this article
TY - JOUR AU - F.U.S. Mattace-Raso AU - N.M. van Popele AU - A. Hofman AU - J.C.M. Witteman PY - 2007 DA - 2007/08/30 TI - 06.02 AORTIC AND CAROTID STIFFNESS IN OLDER ADULTS. THE ROTTERDAM STUDY JO - Artery Research SP - 50 EP - 50 VL - 1 IS - 2 SN - 1876-4401 UR - https://doi.org/10.1016/j.artres.2007.07.047 DO - 10.1016/j.artres.2007.07.047 ID - Mattace-Raso2007 ER -