Artery Research

Volume 6, Issue 4, December 2012, Pages 152 - 152

P1.05 SEDENTARY LIFESTYLE IS ASSOCIATED WITH INDICES OF ARTERIAL STIFFNESS, DIASTOLIC DYSFUNCTION AND OBESITY

Authors
O. Mac Ananey, G. Mellotte, L. Maher, M. Dunne, A. Maher, V. Maher
Dept Cardiology, Adelaide & Meath Hospital incorporating the National Children’s Hospital, Dublin, Ireland
Available Online 17 November 2012.
DOI
10.1016/j.artres.2012.09.042How to use a DOI?
Open Access
This is an open access article distributed under the CC BY-NC license.

The aim of the present study was to examine the relationship between weekly physical activity patterns, obesity and early sub-clinical cardiovascular dysfunction.

For this study, 84 healthy lifelong non-smoking, normotensive subjects (54 male & 30 female) were recruited (age 39±11 years, BMI 25.2±3.3 kg.m2). Weekly physical activity levels were objectively measured over a five day period using triaxial accelerometry (RT3, Stayhealthy, USA). Activity data was categorized as relative time spent being sedentary, lightly active, moderately active and vigorously active1. Body fat composition was estimated using bioelectrical impedance (TBF410GS, Tanita, UK). Augmentation index (AIx, Sphygmacor, Skidmore Medical, UK) and pulse wave velocity (PWV, Vicorder, Skidmore Medical, UK), indices of arterial stiffness, were measured using applanation tonometry. Early/late mitral valve filling velocity (MV E/A) was used to assess cardiac diastolic function (Vivid 7 Dimension, GE, USA).

Mean AIx, PWV, MV E/A ratio, body fat composition were 13.43±14.32 %, 6.79±0.93 m.s−1, 5.11±13.23 and 24.54±7.70 %. Spearman’s correlation analysis identified significant correlations between relative time spent being sedentary and AIx r = 0.3008 p < 0.0054, PWV r = 0.2174 p < 0.0469, MV E/A ratio r = −0.3541 p < 0.027 and % body fat r = 0.3440 p < 0.0017.

The results of the study show that people who spend more time being sedentary have greater body fat, greater arterial stiffness and poorer diastolic function. These observations have important implications for public health.

1.MS Treuth et al., Defining accelerometer thresholds for activity intensities in adolescent girls, Med Sci Sports Exerc, Vol. 36, No. 7, 2004, pp. 1259-66.
Journal
Artery Research
Volume-Issue
6 - 4
Pages
152 - 152
Publication Date
2012/11/17
ISSN (Online)
1876-4401
ISSN (Print)
1872-9312
DOI
10.1016/j.artres.2012.09.042How to use a DOI?
Open Access
This is an open access article distributed under the CC BY-NC license.

Cite this article

TY  - JOUR
AU  - O. Mac Ananey
AU  - G. Mellotte
AU  - L. Maher
AU  - M. Dunne
AU  - A. Maher
AU  - V. Maher
PY  - 2012
DA  - 2012/11/17
TI  - P1.05 SEDENTARY LIFESTYLE IS ASSOCIATED WITH INDICES OF ARTERIAL STIFFNESS, DIASTOLIC DYSFUNCTION AND OBESITY
JO  - Artery Research
SP  - 152
EP  - 152
VL  - 6
IS  - 4
SN  - 1876-4401
UR  - https://doi.org/10.1016/j.artres.2012.09.042
DO  - 10.1016/j.artres.2012.09.042
ID  - MacAnaney2012
ER  -