Artery Research

<Previous Article In Issue
Download article (PDF)
Next Article In Issue>
Volume 4, Issue 4, December 2010, Pages 163 - 163

P4.09 THE INCREASED TRANSMURAL PRESSURE CHANGES A PATTERN OF DILATION REACTION OF MAGISTRAL ARTERIES

Authors
D. Matisone, V. Dzerve, I. Kukulis
Research Institute of Cardiology, University of Latvia, Riga, Latvia
Available Online 2 December 2010.
DOI
10.1016/j.artres.2010.10.061How to use a DOI?
Open Access
This is an open access article distributed under the CC BY-NC license.

Objective: In our previous investigations it was shown that dilatation of magistral arteries (MA) after arterial occlusion (AO) occurs only after the restoration of free blood flow and manifests as an increment of blood flow in the beginning of reactive hyperemia (RH). The aim of this study was to examine whether the increased transmural pressure (Ptransm.) can modulate dilatation reaction of MA after AO.

Design and methods: The investigation was performed on 12 healthy subjects aged between 28–40 yrs. Dilation of MA was appraised from changes in blood flow (I) and haemodynamic resistance (R) in the forearm during RH in two different situations - after 7 min. AO and after 7 min. AO with previous venous congestion (VC). Forearm I was determined by venous occlusion plethysmography. R was calculated from data on I and mean arterial pressure. Systemic arterial pressure was determined auscultatory.

Results: VC before AO of 7 min. abolished the increment of blood flow during RH - maximal I and minimal R was observed just after restoration of free blood flow and normalisation rate of I and R was more rapid than that after 7 min. AO. Maximal I was greater after 7 min. AO with previous VC than that after 7 min. AO (42±1,4 and 33±1,6 ml/100cm3/min., correspondingly) and minimal R was smaller after 7 min. AO with previous VC than that after 7 min. AO (2,25±0,1 and 2,7±0,2 PRU100, correspondingly).

Conclusion: The increase of Ptransm. changes a patern of dilatation reaction of forearm magistral arteries.

<Previous Article In Issue
Download article (PDF)
Next Article In Issue>
Journal
Artery Research
Volume-Issue
4 - 4
Pages
163 - 163
Publication Date
2010/12/02
ISSN (Online)
1876-4401
ISSN (Print)
1872-9312
DOI
10.1016/j.artres.2010.10.061How to use a DOI?
Open Access
This is an open access article distributed under the CC BY-NC license.

Cite this article

risenwbib
TY  - JOUR
AU  - D. Matisone
AU  - V. Dzerve
AU  - I. Kukulis
PY  - 2010
DA  - 2010/12/02
TI  - P4.09 THE INCREASED TRANSMURAL PRESSURE CHANGES A PATTERN OF DILATION REACTION OF MAGISTRAL ARTERIES
JO  - Artery Research
SP  - 163
EP  - 163
VL  - 4
IS  - 4
SN  - 1876-4401
UR  - https://doi.org/10.1016/j.artres.2010.10.061
DO  - 10.1016/j.artres.2010.10.061
ID  - Matisone2010
ER  -