Artery Research

Volume 4, Issue 4, December 2010, Pages 164 - 164

P5.01 INCREMENTAL PREDICTIVE VALUE OF POOR PENILE ARTERIAL FLOW AS AN ADJUNCT TO INCREASED AORTIC STIFFNESS FOR DETECTING MYOCARDIAL ISCHEMIA DURING STRESS ECHOCARDIOGRAPHY IN ERECTILE DYSFUNCTION PATIENTS

Authors
D. Terentes-Printzios, C. Vlachopoulos, N. Ioakeimidis, K. Rokkas, N. Alexopoulos, A. Samentzas, A. Aggelis, A. Siama, P. Xaplanteris, C. Stefanadis
Hippokrateion Hospital, 1st Department of Cardiology, Athens Medical School, Athens, Greece
Available Online 2 December 2010.
DOI
10.1016/j.artres.2010.10.063How to use a DOI?
Open Access
This is an open access article distributed under the CC BY-NC license.

Introduction: Erectile dysfunction (ED) may be considered a clinical manifestation of a generalized vascular disease affecting also the penile arteries. The aim of this prospective study was to investigate arterial function determinants of wall motion abnormalities during stress testing in men with ED.

Methods: 188 consecutive asymptomatic men (40–60 y/o), with non-psychogenic and non-hormonal ED underwent:(1) dobutamine stress echocardiography (DSE) (2) evaluation of aortic stiffness with carotid-femoral pulse wave velocity (PWV) and (3) penile vascular assessment using color duplex sonography. Criteria of positivity were regional dysfunction >2 segments demonstrated by DSE. A mean peak systolic velocity (PSV) below 25 cm/sec was considered to indicate severe arterial insufficiency.

Results: 49 ED patients (26 %) exhibited regional wall motion abnormalities. Men with abnormal DSE compared to men without stress evidence for myocardial ischemia had higher prevalence of multiple cardiovascular risk factor status (> 2 risk factors) (36 vs 22 %, P<0.001), higher PWV (8.8 ± 1.2 vs 8.1±1.3 m/s, P<0.01) and lower penile Doppler velocities (28.2±8 vs 33.9±9 cm/s, P<0.001). Receiver operating characteristic curve analysis for the prediction of DSE positivity showed that PWV value > 8.2 m/s combined with PSV<26.5 cm/s was the best predictor of DSE positivity (61 % sensitivity, 82% specificity, and 83% positive predictive value).

Conclusion: In asymptomatic men with ED increased PWV and decreased PSV values correlate significantly with an increased likelihood of exhibiting regional wall motion abnormalities during DSE and the greatest gain is found in men with severe penile arterial insufficiency and a stiffer aorta.

Journal
Artery Research
Volume-Issue
4 - 4
Pages
164 - 164
Publication Date
2010/12/02
ISSN (Online)
1876-4401
ISSN (Print)
1872-9312
DOI
10.1016/j.artres.2010.10.063How to use a DOI?
Open Access
This is an open access article distributed under the CC BY-NC license.

Cite this article

TY  - JOUR
AU  - D. Terentes-Printzios
AU  - C. Vlachopoulos
AU  - N. Ioakeimidis
AU  - K. Rokkas
AU  - N. Alexopoulos
AU  - A. Samentzas
AU  - A. Aggelis
AU  - A. Siama
AU  - P. Xaplanteris
AU  - C. Stefanadis
PY  - 2010
DA  - 2010/12/02
TI  - P5.01 INCREMENTAL PREDICTIVE VALUE OF POOR PENILE ARTERIAL FLOW AS AN ADJUNCT TO INCREASED AORTIC STIFFNESS FOR DETECTING MYOCARDIAL ISCHEMIA DURING STRESS ECHOCARDIOGRAPHY IN ERECTILE DYSFUNCTION PATIENTS
JO  - Artery Research
SP  - 164
EP  - 164
VL  - 4
IS  - 4
SN  - 1876-4401
UR  - https://doi.org/10.1016/j.artres.2010.10.063
DO  - 10.1016/j.artres.2010.10.063
ID  - Terentes-Printzios2010
ER  -