P8.5 EVALUATION OF VALVULOARTERIAL IMPEDANCE IN AORTIC VALVE STENOSIS BY USING CARDIAC MAGNETIC RESONANCE AND CAROTID ARTERY TONOMETRY

G. Soulat; E. Bollache; F. Pontnau; L. Perdrix; V. Zhygalina; P. Achouh; N. Kachenoura; P. Boutouyrie; S. Laurent; E. Mousseaux

doi:10.1016/j.artres.2014.09.180

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Volume 8, Issue 4, December 2014, Pages 152 - 152

P8.5 EVALUATION OF VALVULOARTERIAL IMPEDANCE IN AORTIC VALVE STENOSIS BY USING CARDIAC MAGNETIC RESONANCE AND CAROTID ARTERY TONOMETRY

Authors

G. Soulat^a^{, b}, E. Bollache^c, F. Pontnau^a, L. Perdrix^a, V. Zhygalina^a, P. Achouh^a, N. Kachenoura^c, P. Boutouyrie^a^{, b}, S. Laurent^a^{, b}, E. Mousseaux^a^{, b}

^aEuropean Hospital Georges Pompidou, Paris, France

^bParis Decartes University, Paris, France

^cPierre and Marie Curie University, Paris, France

Available Online 4 November 2014.

DOI: 10.1016/j.artres.2014.09.180 How to use a DOI?
Open Access: This is an open access article distributed under the CC BY-NC license.

In aortic valve stenosis (AVS), valvuloarterial impedance (Zva), as left ventricle (LV) afterload estimation, has been proposed in echocardiography (TTE) to predict adverse outcome better than conventional parameters such as aortic valve area (AVA). However its calculation method differs from standard temporal arterial characteristic impedance (Zc) assessment. The aim of our study was to apply the Zc concept of measurements to estimate Zva by using phase contrast magnetic resonance (PC-MR) and carotid tonometry.

Methods: 40 patients (76±13 years, 21 males) underwent MR with carotid tonometry and TTE.

-Zva-TTE was assessed with brachial systolic arterial pressure, TTE transvalvular mean gradient and stroke volume index to body surface area.

-Zva-MR was assessed with pressure waveform from carotid tonometry, transvalvular pressure gradient and Flow waveform on LV outflow track from PC-MR.

These methods were evaluated by comparing their links with diastolic dysfunction estimated by TTE E/Ea ratio.

Results: Zva values were higher in symptomatic patients using both TTE and MR. In univariate analysis, only Zva-MR was correlated with E/Ea (r=0,5, p=0,001).

In multivariate analysis of determinants of E/Ea, a significant model including age, Mean blood pressure, LV ejection fraction, LV mass and AVA was obtained (R2=0,41; p<0,01).When Zva-MR was included, the overall significance of the model was higher (R2=0,56;p<0,01). Only Zva-MR and LV Mass remained independently correlated to E/Ea.

Conclusions: By using MR in association with carotid tonometry, the calculation of Zva is feasible and can improve LV afterload assessment in AVS. This new way to estimate Zva may be clinically useful in patients evaluation.

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Journal: Artery Research
Volume-Issue: 8 - 4
Pages: 152 - 152
Publication Date: 2014/11/04
ISSN (Online): 1876-4401
ISSN (Print): 1872-9312
DOI: 10.1016/j.artres.2014.09.180 How to use a DOI?
Open Access: This is an open access article distributed under the CC BY-NC license.

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ris enw bib

TY  - JOUR
AU  - G. Soulat
AU  - E. Bollache
AU  - F. Pontnau
AU  - L. Perdrix
AU  - V. Zhygalina
AU  - P. Achouh
AU  - N. Kachenoura
AU  - P. Boutouyrie
AU  - S. Laurent
AU  - E. Mousseaux
PY  - 2014
DA  - 2014/11/04
TI  - P8.5 EVALUATION OF VALVULOARTERIAL IMPEDANCE IN AORTIC VALVE STENOSIS BY USING CARDIAC MAGNETIC RESONANCE AND CAROTID ARTERY TONOMETRY
JO  - Artery Research
SP  - 152
EP  - 152
VL  - 8
IS  - 4
SN  - 1876-4401
UR  - https://doi.org/10.1016/j.artres.2014.09.180
DO  - 10.1016/j.artres.2014.09.180
ID  - Soulat2014
ER  -

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