(AIx) is a new method that extends understanding of the characteristics of BP and arterial properties. The aim of the study was to explore gender differences on AM of central BP and AIx in different age groups.

Methods: Successful AM of brachial and central BP was done with oscillometric BPLab VASOTENS system (OOO Petr Telegin, Russia) in 84 untreated hypertensive subjects (55,8±9,6 years, male 36,9 %). Gender differences of central BP and AIx were evaluated in patients <55 (14 men, 23 women), 55–60 (7 men, 16 women), 61–70 years (10 men, 14 women). Differences were considered significant if p<0,05.

Results: Several findings were consistent among all age groups. First, men had slightly higher levels of brachial and aortic SBP than women: respectively, <55 years brachial SBP day/night 144±14/134±20 vs 137±16/128±16, 55–60 years 147±18/146±21 vs 139±16/132±22, 61–70 years 141±23/135±32 vs 137±14/129±17 mmHg. Second, nocturnal decline of brachial and aortic SBP was greater in women than in men: respectively, <55 years aortic SBP day/night 128±15/121±15 vs 132±14/132±14, 55–60 years 130±15/124±21 vs 134±17/137±19, 61–70 years 128±14/122±16 vs 131±22/127±29 mmHg. Third, women had a higher AIx@HR75 in all time periods but night increase AIx was significantly more evident in men: respectively, AIx (day-night)/day (%) <55 years −44±12 in men vs −22±7,0 in women, 55–60 years −38±18 vs −20±16, respectively, 61–70 years −45±19 vs −19±10, respectively (p<0,05 for all ages).

Conclusion: Gender differences in characteristics of AIx and its diurnal variation were identified and should be considered when analyzing the results of AM of central BP