12.17 SYSTOLIC AMBULATORY BLOOD PRESSURE IS MORE CLOSELY RELATED TO LEFT VENTRICULAR HYPERTROPHY THAN CENTRAL AORTIC AND BRACHIAL BLOOD PRESSURE IN NEVER TREATED HYPERTENSIVE PATIENTS
- DOI
- 10.1016/j.artres.2011.10.200How to use a DOI?
- Keywords
- arterial stiffness; central aortic pressure; left ventricular hypertrophy
- Open Access
- This is an open access article distributed under the CC BY-NC license.
Background: Our purpose was to assess the relationship between left ventricular mass (LVM) and three different ways to measure blood pressure in hypertensive patients.
Methods: Cross-sectional study that included non-diabetic, untreated hypertensive patients. Central aortic pressure (CAP), derived from pulse wave analysis (SphygmoCor-System), office brachial blood pressure (oBBP) and ambulatory 24-hour blood pressure (ABP) were obtained. LVM was determined by standard echocardiography (cut-off values for left ventricular hypertrophy (LVH) were 125 g/m2 for men and 110 g/m2 for women).
Results: The study population comprised 418 (229 men, with mean age, 49±13 years). Of the participants, 126 (30%) had LVH. Patients with LVH were older [52(13) vs. 47(12) years; p<0.001], had higher values of systolic oBBP [151(18) vs. 143 (16) mm Hg ;p=0.001 ], CAP [141(18) vs. 132 (16) mm Hg;p=0.03 ], and systolic ABP [139(14) vs. 131 (9) mm Hg ;p=0.001].
Stepwise regression analysis corrected by age, gender and presence of metabolic syndrome, revealed that systolic BP (β= 0,0001, p<0,001), systolic CAP (β= 0,002, p<0,001), and systolic ABP (β= 0,001, p<0,001) were all significantly related to LVH.
In a logistic multivariate regression analysis, dividing LV mass in tertiles, systolic CAP (OR: 2,1;95% CI,1,2–3,7; p= 0,01), and systolic ABPM-values (OR:3,21;95% CI,1,8–5,7; p=0,001), but not brachial BP, were associated with LVH.
Conclusions: In untreated hypertensives, LVH is closer related to CAP than to office brachial BP, but systolic ABP-values show the best association to the prevalence of LVH.
Cite this article
TY - JOUR AU - E. Rodilla Sala AU - J.M. Pascual Izuel AU - J.A. Costa Muñoz AU - F. Pérez Lahiguera AU - J. Cardona AU - S. Tejero PY - 2011 DA - 2011/11/29 TI - 12.17 SYSTOLIC AMBULATORY BLOOD PRESSURE IS MORE CLOSELY RELATED TO LEFT VENTRICULAR HYPERTROPHY THAN CENTRAL AORTIC AND BRACHIAL BLOOD PRESSURE IN NEVER TREATED HYPERTENSIVE PATIENTS JO - Artery Research SP - 204 EP - 204 VL - 5 IS - 4 SN - 1876-4401 UR - https://doi.org/10.1016/j.artres.2011.10.200 DO - 10.1016/j.artres.2011.10.200 ID - RodillaSala2011 ER -