Artery Research

<Previous Article In Issue
Download article (PDF)
Next Article In Issue>
Volume 5, Issue 4, December 2011, Pages 173 - 173

P6.07 POPSCORE: A NEW INDEX TO EVALUATE ARTERIAL AGEING INDEPENDENTLY OF ARTERIAL BLOOD PRESSURE

Authors
M. Hallab, J.M. Boin, M. Tramblay, P. Chevalet
CHU de Nantes, Nantes, France
Available Online 29 November 2011.
DOI
10.1016/j.artres.2011.10.092How to use a DOI?
Open Access
This is an open access article distributed under the CC BY-NC license.

Hypothesis: PWV don’t correlate with age in the upper limb but in the aorta and lower limb.

Aim: To study the relationship between ageing and indices based on pulse wave transit time (PWTT) between the toe and the finger.

Material and methods: measurements were performed in 300 patients in primary care and occupational practice, after 5 minutes of supine rest using a new device (pOpmètre® - Axelife SAS - France) which measures the toe and finger PWTT relative to R-ECG wave. Difference of PWTT between the toe and finger (DTF) was computed and, using a chart based on body height, we calculated the PWVtf [PWVtf = k *subject’s height / DTF] and the pOpscore® (toePWV / fingerPWV) indices.

Results: Of the tested 300 patients, 147 (93 men and 54 women aged 45yrs ± 2 vs. 40yrs ± 2, p=0.048 respectively) with 0 or only 1 conventional risk factor and without known POAD or Vasodilator therapy.

Sex anova (F; p) Age (years) (r2; p) Weight (Kg) (r2; p) Height (cm) (r2; p) SBP (mmHg) (r2; p) DBP (mmHg) (r2; p) MBP (mmHg) (r2; p) BMI (Kg/m2) (r2; p)
DTF (sec) 0.01;ns 0.69;10−4 0.001;ns 0.02;0.08 0.29;10−4 0.07;10−3 0.18; 10−4 0.04;0.01
PWVtf (m/s) 0.10;ns 0.69;10−4 0.003;ns 0.01;ns 0.22;10−4 0.03;0.02 0.12; 10−4 0.014; ns
pOpscore® 0.04;ns 0.60;10−4 0.008;ns 0.01;ns 0.23;10−4 0.07;10−3 0.15; 10−4 0.02;0.04

Using stepwise regression analysis, (variables to enter: Age, BMI, SBP, DBP, MBP), 1) DTF was dependent with age (p <0.0001) and SBP (p <0.01); 2) PWVtf with age (p <0.0001), SBP (p <0.01) and DBP (p <0.05); 3) pOpscore® was dependent only with age (p <0.0001) not with SBP (p > 0.07).

Conclusion: In this study,

  1. 1-

    All variables were correlated to age and blood pressure.

  2. 2-

    pOpscore® is related only to ageing independently from blood pressure.

  3. 3-

    pOpmètre® is a promising technique for the routine determination of vascular ageing in primary care medicine.

<Previous Article In Issue
Download article (PDF)
Next Article In Issue>
Journal
Artery Research
Volume-Issue
5 - 4
Pages
173 - 173
Publication Date
2011/11/29
ISSN (Online)
1876-4401
ISSN (Print)
1872-9312
DOI
10.1016/j.artres.2011.10.092How to use a DOI?
Open Access
This is an open access article distributed under the CC BY-NC license.

Cite this article

risenwbib
TY  - JOUR
AU  - M. Hallab
AU  - J.M. Boin
AU  - M. Tramblay
AU  - P. Chevalet
PY  - 2011
DA  - 2011/11/29
TI  - P6.07 POPSCORE: A NEW INDEX TO EVALUATE ARTERIAL AGEING INDEPENDENTLY OF ARTERIAL BLOOD PRESSURE
JO  - Artery Research
SP  - 173
EP  - 173
VL  - 5
IS  - 4
SN  - 1876-4401
UR  - https://doi.org/10.1016/j.artres.2011.10.092
DO  - 10.1016/j.artres.2011.10.092
ID  - Hallab2011
ER  -