P4.12 MODEL BASED ESTIMATION OF AORTIC PULSE WAVE VELOCITY
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- 10.1016/j.artres.2011.10.056How to use a DOI?
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The proposed model is inspired by the theoretical frameworks of (1) Moens-Korteweg, (2) Bramwell & Hill, (3) Waterhammer equation used in ARCSolver. All of the mentioned equations allow the determination of velocity in an elastic tube from a single point measurement. Whereby Moens-Korteweg consider the tension of the wall and the radius of the vessel as well as the viscosity of blood which can be assumed constant and near one in the human circulation for simplicity. It’s now not really surprising that with increasing pressure both wall tension and wall radius will elevate. In younger age both parameters likely to the same extent and with only minor effects on PWV. With increasing age distensibility of the arterial wall degenerates. Subsequently an increase in pressure will not be compensated by a diameter change, even more tension within the wall will increase and PWV as well. All changes affect PWV non linear. Equation 2 rewrites equation 1 to consider observable variables like pressure and volume flow. Simply spoken, PWV is a result of pressure changes and volume displacement. In complex transmission line theory using Fourier analysis, the relation between arterial flow and blood pressure is described by the so called characteristic impedance (Zc) illustrated in the Waterhammer Equation (3). ARCSolver calculates (Zc) using an adopted Windkessel model. Determinants of ARCSolver-PWV are wall tension (impedance), aortic blood pressure and age.
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TY - JOUR AU - S. Wassertheurer AU - B. Hametner AU - T. Weber PY - 2011 DA - 2011/11/29 TI - P4.12 MODEL BASED ESTIMATION OF AORTIC PULSE WAVE VELOCITY JO - Artery Research SP - 162 EP - 162 VL - 5 IS - 4 SN - 1876-4401 UR - https://doi.org/10.1016/j.artres.2011.10.056 DO - 10.1016/j.artres.2011.10.056 ID - Wassertheurer2011 ER -