P3.08 EFFECTS OF REGULAR LEISURE EXERCISE ON ARTERIAL PRESSURE AUGMENTATION. THE MONICA/KORA AUGSBURG STUDY

M.R.P. Markus; J. Stritzke; W. Lieb; A. Luchner; A. Döring; U. Keil; H. Schunkert; H.W. Hense

doi:10.1016/j.artres.2009.10.037

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Volume 3, Issue 4, December 2009, Pages 182 - 182

P3.08 EFFECTS OF REGULAR LEISURE EXERCISE ON ARTERIAL PRESSURE AUGMENTATION. THE MONICA/KORA AUGSBURG STUDY

Authors

M.R.P. Markus¹, J. Stritzke¹, W. Lieb¹, A. Luchner², A. Döring³, U. Keil⁴, H. Schunkert¹, H.W. Hense⁴

¹Medical Clinic II, University of Lübeck Medical School, Lübeck, Germany

²Clinic and Policlinic for Internal Medicine II, University Hospital of Regensburg, Regensburg, Germany

³Institute of Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg, Germany

⁴Institute of Epidemiology and Social Medicine, University of Münster, Münster, Germany

Available Online 3 December 2009.

DOI: 10.1016/j.artres.2009.10.037 How to use a DOI?
Abstract: Background: Exercise influences pulse wave morphology, but the mechanisms are unknown.

Methods: We measured radial arterial pulse wave contour (SphygmoCorR) in 1005 adults from a cohort follow-up examination in 2004/5 and compared individuals who, by self report, were sedentary (NPE, of less than one hour of aerobic exercise per week, n=130) or who practiced irregular physical exercise (IPE, irregularly at least one hour of aerobic exercise per week, n=204) or regular physical exercise (RPE, regularly at least two hours of aerobic exercise per week, n=111). Aortic augmentation was evaluated using multivariate regression modeling. Individuals with intake of antihypertensive or hormonal medications were excluded.

Results: After adjustment for concomitant factors, like gender, age, height2.7, total body weight, heart rate, central mean blood pressure and number of cigars consumed per day, lack of regular physical exercise was significantly associated to aortic augmentation, with 8.68 mmHg among NPE versus 7.68 mmHg in the IPE (p=0.035) and 6.84 mmHg in the RPE group (p=0.001). Likewise, the respective augmentation indexes were 22.9% (p=0.003), 22.5% (p=0,004) and 19.6%. Moreover, the RPE group presented the highest reflected wave travel time (RTT=144.9msec vs. 141.7 msec in IPE and 141.3 msec in NPE; p=0.012 and 0.014, respectively).

Conclusions: Leisure exercise seems to be related to less aortic pressure augmentation and a longer reflected wave traveling time, an effect that potentially enhances ventricular-vascular coupling and reduces the after-load of the left ventricle.
Open Access: This is an open access article distributed under the CC BY-NC license.

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Journal: Artery Research
Volume-Issue: 3 - 4
Pages: 182 - 182
Publication Date: 2009/12/03
ISSN (Online): 1876-4401
ISSN (Print): 1872-9312
DOI: 10.1016/j.artres.2009.10.037 How to use a DOI?
Open Access: This is an open access article distributed under the CC BY-NC license.

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ris enw bib

TY  - JOUR
AU  - M.R.P. Markus
AU  - J. Stritzke
AU  - W. Lieb
AU  - A. Luchner
AU  - A. Döring
AU  - U. Keil
AU  - H. Schunkert
AU  - H.W. Hense
PY  - 2009
DA  - 2009/12/03
TI  - P3.08 EFFECTS OF REGULAR LEISURE EXERCISE ON ARTERIAL PRESSURE AUGMENTATION. THE MONICA/KORA AUGSBURG STUDY
JO  - Artery Research
SP  - 182
EP  - 182
VL  - 3
IS  - 4
SN  - 1876-4401
UR  - https://doi.org/10.1016/j.artres.2009.10.037
DO  - 10.1016/j.artres.2009.10.037
ID  - Markus2009
ER  -

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