Artery Research

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Volume 3, Issue 4, December 2009, Pages 189 - 190

P8.13 CORONARY IMPLANTATION OF SIROLIMUS-ELUTING STENT IMPAIRS THE PERIPHERAL VASCULAR COMPLIANCE IN PATIENT WITH CORONARY ARTERY DISEASE

Authors
M. Vatrano, R. Ceravolo, C. Nesta, A. Ferraro, E. Campopiano, F. Borrello, V. Pascale, G. Ciconte, V.A. Ciconte
Haemodinamic and Interventional Cardiologic Unit. “Pugliese – Ciaccio” Hospital of Catanzaro, Catanzaro, Italy
Available Online 3 December 2009.
DOI
10.1016/j.artres.2009.10.119How to use a DOI?
Abstract

Introduction: To the best of our knowledge, any studies evaluated potential influence on peripheral arterial stiffness, measured by pulse wave velocity (PWV), of percoutaneous coronary intervention (PCI) and stenting.

Methods: 150 patients were enrolled and underwent coronary angiography. In 68 patients was performed coronary stenting (PCI group). PWV was invasively obtained before and after coronary stenting.

Results: Coronary stenting produced a significant augment of PWV (from 4.59 to 5.82m/s, P=0.000). In contrast, the sub-population which performed angiography without PCI (noPCI group), didn’t show any significant change in PWV. The analysis of PCI group demonstrated that only implantation of Sirolimus eluting stent (SES) caused a significant increase of PWV (from 4.62 to 6.15m/s, P=0.029). In a stepwise multiple regression model stent length, glycaemia and body mass index were significantly associated with increase of PWV, accounting for a total of 51.7% of the variation (P=0.009). In particular, stent length accounted for 39.6% of the variance in PWV augmentation; glycaemia and body mass index explained an additional 12.1% of its variability. In the same analysis performed in PCI group, stent length accounted for 65.3% of the variance (P=0.024) and other than glycaemia and body mass index, also implantation of SES explained an additional 18.5%.

Conclusion: We have shown, for the first time, a significant association between SES implantation and an central stiffness worsening.

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This is an open access article distributed under the CC BY-NC license.

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Journal
Artery Research
Volume-Issue
3 - 4
Pages
189 - 190
Publication Date
2009/12/03
ISSN (Online)
1876-4401
ISSN (Print)
1872-9312
DOI
10.1016/j.artres.2009.10.119How to use a DOI?
Open Access
This is an open access article distributed under the CC BY-NC license.

Cite this article

risenwbib
TY  - JOUR
AU  - M. Vatrano
AU  - R. Ceravolo
AU  - C. Nesta
AU  - A. Ferraro
AU  - E. Campopiano
AU  - F. Borrello
AU  - V. Pascale
AU  - G. Ciconte
AU  - V.A. Ciconte
PY  - 2009
DA  - 2009/12/03
TI  - P8.13 CORONARY IMPLANTATION OF SIROLIMUS-ELUTING STENT IMPAIRS THE PERIPHERAL VASCULAR COMPLIANCE IN PATIENT WITH CORONARY ARTERY DISEASE
JO  - Artery Research
SP  - 189
EP  - 190
VL  - 3
IS  - 4
SN  - 1876-4401
UR  - https://doi.org/10.1016/j.artres.2009.10.119
DO  - 10.1016/j.artres.2009.10.119
ID  - Vatrano2009
ER  -