Artery Research

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Volume 9, Issue C, March 2015, Pages 27 - 32

Impact of obesity on aortic root calcification and coronary calcification using multi-detector CT

Authors
Hussein Nafakhia, *, Hasan A. Al-Nafakhb, Abdulameer A. Al-Mosawib
aInternal Medicine Department, AL-Sader Teaching Hospital, Medicine College, Kufa University, Najaf, Iraq
bRadiology Department, Medicine College, Kufa University, Iraq
*Corresponding author. Internal Medicine Department, Medicine College, Kufa University, P.O. 21, Kufa, Najaf, Iraq. Tel.: +964 78 218 41 16; fax: +964 34 09 52. E-mail address: husseinaf.alnaffakh@uokufa.edu.iq (H. Nafakhi).
Corresponding Author
Hussein Nafakhi
Received 30 September 2014, Revised 20 November 2014, Accepted 12 December 2014, Available Online 24 December 2014.
DOI
10.1016/j.artres.2014.12.001How to use a DOI?
Keywords
Obesity; BMI; Coronary calcification; Aortic root calcification; MDCT
Abstract

Objective: The impact of obesity measured by BMI on cardiovascular diseases remains controversial. We investigated the impact of obesity measured by BMI on the prevalence and correlation of aortic root calcification (ARC) and coronary artery calcification (CAC) in patients assessed by multi-detector CT (MDCT) angiography.

Materials and methods: A total of 175 patients with intermediate pretest probability of ischemic heart disease based on age, sex, and symptoms who referred from cardiology clinic to 64-MDCT angiography examination for assessment of coronary artery disease were eligible for enrollment in this cross sectional study. The patients were divided into 2 groups according to their BMI. Non obese group (BMI < 25) composed of 73 (42%) patients (male 41 (56%), female 32 (44%) with a mean age 55 ± 8 years. Obese group (BMI ≥ 25) composed of 102 (58%) patients (male 45 (44%), female 58 (56%) with mean age 56 ± 7 years).

Results: ARC was significantly associated with coronary artery calcification pattern in both non obese and obese groups (r = 461, P = 0.000) and (r = 0.358, P = 0.000) respectively. The significant association between ARC and CAC persisted even after adjustment for age, hypertension, smoking, hyperlipdemia and presence of multiple cardiac risk factor in both non obese and obese groups (95% C.I. = 0.106, 0.259, P = 0.000) and (95% C.I. = 0.108, 0.610, P = 0.006) respectively.

Conclusion: ARC was significantly correlated with CAC irrespective of BMI status.

Copyright
© 2014 Association for Research into Arterial Structure and Physiology. Published by Elsevier B.V. All rights reserved.
Open Access
This is an open access article distributed under the CC BY-NC license.

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<Previous Article In Issue
Next Article In Issue>
Journal
Artery Research
Volume-Issue
9 - C
Pages
27 - 32
Publication Date
2014/12/24
ISSN (Online)
1876-4401
ISSN (Print)
1872-9312
DOI
10.1016/j.artres.2014.12.001How to use a DOI?
Copyright
© 2014 Association for Research into Arterial Structure and Physiology. Published by Elsevier B.V. All rights reserved.
Open Access
This is an open access article distributed under the CC BY-NC license.

Cite this article

risenwbib
TY  - JOUR
AU  - Hussein Nafakhi
AU  - Hasan A. Al-Nafakh
AU  - Abdulameer A. Al-Mosawi
PY  - 2014
DA  - 2014/12/24
TI  - Impact of obesity on aortic root calcification and coronary calcification using multi-detector CT
JO  - Artery Research
SP  - 27
EP  - 32
VL  - 9
IS  - C
SN  - 1876-4401
UR  - https://doi.org/10.1016/j.artres.2014.12.001
DO  - 10.1016/j.artres.2014.12.001
ID  - Nafakhi2014
ER  -