Assessment of Arterial Stiffness by Brachial Oscillometry in Community Pharmacies for Managing Hypertension (COPHARTEN)☆

Authors

Enrique Rodilla^{1, *, †,} , Rosa Prats^2, , Otón Bellver^2, , Javier Reig^2, , Pedro Cunha^{3, †,} , María Teresa Climent^2,

¹Departamento de Ciencias de la Salud, Hospital Universitario de Sagunto, Universidad Cardenal Herrera-CEU, CEU Universities, Valencia, Spain

²Sociedad Española de Farmacia Familiar y Comunitaria (SEFAC), Madrid, Spain

³Escola de Medicina, School of Medicine, University of Minho, Braga, Portugal

^†

Iberian Network on Arterial Structure, Central Hemodynamics and Neurocognition, Universidade do Minho, Department Escola de Medicina, Braga, Portugal.

^*Corresponding author. Email: enrique.rodilla@uchceu.es

DOI

10.2991/artres.k.191124.001How to use a DOI?

Keywords

Arterial stiffness; target organ damage; pulse wave velocity; brachial oscillometry; prehypertension; community pharmacies

Abstract

Background and Objective: Arterial Stiffness (AS) measured as pulse wave velocity has emerged in recent years as a hypertension mediated organ damage with independent prognostic value for Cardiovascular (CV) diseases that has also been discussed as a potential cause of Hypertension (HTN). The aim of this study is to (1) evaluate how measurement of AS modifies CV risk calculation by SCORE, (2) to measure the predictive value of AS for incident hypertension in normotensive patients, and (3) to analyze the association between control of HTN and presence of AS in sustained HTN.

Patients and Methods: A longitudinal, prospective, observational trial under conditions of daily pharmaceutical and clinical practice will be conducted in approximately 60 community pharmacies of the Iberian Peninsula in normotensive and/or hypertensive patients entering a pharmacy spontaneously. In the first cross-sectional step, AS will be estimated with a semi-automatic, validated device (Mobil-O-Graph^®, IEM), followed by a 10-item questionnaire. The patients will be referred to Primary Care for stratifying risk by SCORE tables and standard evaluation. In the second longitudinal step, patients will be asked to repeat the visit after 12 months.

Discussion: This study aims to improve CV risk stratification and to investigate the potential of AS in predicting incident HTN in normotensive subjects. Besides, it will analyze the role of arterial stiffness as an associated factor to prevent control in sustained HTN in a setting of cooperation between community pharmacies and physicians in daily clinical practice.

Copyright

© 2019 Association for Research into Arterial Structure and Physiology. Publishing services by Atlantis Press International B.V.

Open Access

This is an open access article distributed under the CC BY-NC 4.0 license (http://creativecommons.org/licenses/by-nc/4.0/).

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TY  - JOUR
AU  - Enrique Rodilla
AU  - Rosa Prats
AU  - Otón Bellver
AU  - Javier Reig
AU  - Pedro Cunha
AU  - María Teresa Climent
PY  - 2019
DA  - 2019/12/05
TI  - Assessment of Arterial Stiffness by Brachial Oscillometry in Community Pharmacies for Managing Hypertension (COPHARTEN)☆
JO  - Artery Research
SP  - 121
EP  - 130
VL  - 25
IS  - 3-4
SN  - 1876-4401
UR  - https://doi.org/10.2991/artres.k.191124.001
DO  - 10.2991/artres.k.191124.001
ID  - Rodilla2019
ER  -