Practical solutions for hypertensive patients with dyslipidemia☆
This article was presented as lecture in the symposium on “Protecting arteries against hypertension and dyslipidemia” at the ARTERY 16 Congress in Copenhagen, Denmark (October 13–15, 2016).
- DOI
- 10.1016/j.artres.2017.03.002How to use a DOI?
- Keywords
- ACE inhibitors; Amlodipine; Aortic stiffness; Central pressures; Dyslipidemia; Hypertension
- Abstract
Arterial hypertension and dyslipidemia often coexist and constitute major risk factors of ischemic heart disease. Aggressive treatment of both comorbidities is of paramount importance to decrease global risk. Low adherence is a determinant of poor risk factor control and increases adverse cardiovascular outcomes. Regarding treatment of hypertension, combination therapy is superior in achieving target BP values compared to up-titrating monotherapy and it is recommended in hypertension guidelines. The combined use of drugs in a single pill formulation increases adherence and reduces cardiovascular risk. Our review of the literature indicates that triple therapy with an angiotensin converting enzyme inhibitor, a calcium channel blocker and a statin is associated with a significant reduction in major cardiovascular events. This is attributed to synergy at the vascular, and is translated into efficacy at the clinical level.
- Copyright
- © 2017 Association for Research into Arterial Structure and Physiology. Published by Elsevier B.V. All rights reserved.
- Open Access
- This is an open access article distributed under the CC BY-NC license.
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TY - JOUR AU - Charalambos Vlachopoulos AU - Nikolaos Ioakeimidis PY - 2017 DA - 2017/04/05 TI - Practical solutions for hypertensive patients with dyslipidemia☆ JO - Artery Research SP - 49 EP - 54 VL - 18 IS - C SN - 1876-4401 UR - https://doi.org/10.1016/j.artres.2017.03.002 DO - 10.1016/j.artres.2017.03.002 ID - Vlachopoulos2017 ER -