Artery Research

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Volume 22, Issue C, June 2018, Pages 43 - 48

Study of atherosclerosis in abdominal aortic aneurysms of autopsied patients

Authors
Maria Helena Soaresa, Mariana Silva Oliveiraa, Aline Cristina Souza da Silvaa, *, Bianca Gonçalves Silva Torquatoa, Gabriela Ribeiro Julianob, Guilherme Ribeiro Julianoe, Márcia Fernandes de Araújob, Camila Lourencini Cavellanic, Lívia Ferreira Oliveirad, Mara Lúcia Fonseca Ferraze, Vicente de Paula Antunes Teixeirae
aHealth Science, Concentration Area Human Pathology, Triangulo Mineiro Federal University, Uberaba, Minas Gerais, Brazil
bHealth Sciences, Concentration Area Basic and Experimental Pathology, Triangulo Mineiro Federal University, Uberaba, Minas Gerais, Brazil
cPathology, Health Sciences Institute, Triangulo Mineiro Federal University, Uberaba, Minas Gerais, Brazil
dBasic Instruments Nursing Discipline, Uberlandia Federal University, Uberlandia, Minas Gerais, Brazil
eTriangulo Mineiro Federal University, Uberaba, Minas Gerais, Brazil
*Corresponding author. General Pathology Discipline, Triangulo Mineiro Federal University, St. Frei Paulino, 30, 38025-180, Uberaba, Minas Gerais, Brazil. Fax: +55 34 3318 5846. E-mail addresses: mhmais@hotmail.com (M.H. Soares), maholiveira7@hotmail.com (M.S. Oliveira), aline.souza_1@hotmail.com (A.C.S. da Silva), biatorquato@gmail.com (B.G.S. Torquato), gabrielaribeiro91@hotmail.com (G.R. Juliano), guiribeiro85@yahoo.com.br (G.R. Juliano), marciaearaujo@yahoo.com.br (M.F. de Araújo), camila.cavellani@uftm.edu.br (C.L. Cavellani), liviaenfermg@yahoo.com.br (L.F. Oliveira), mara.ferraz@uftm.edu.br (M.L.F. Ferraz), vicenteantunes54@gmail.com (V. de Paula Antunes Teixeira).
Corresponding Author
Aline Cristina Souza da Silva
Received 21 February 2018, Revised 13 April 2018, Accepted 18 April 2018, Available Online 5 May 2018.
DOI
10.1016/j.artres.2018.04.003How to use a DOI?
Keywords
Atherosclerosis; Aorta; Autopsy; Collagen
Abstract

Background: Any kind of change in the arterial wall as atherosclerosis, may be the etiologic agent of the formation of aneurysm in an artery. The aim of this study was to describe the morphological and morphometric characteristics of the aorta with aneurysm in autopsied patients in relation to age, gender, white and non-white patients and the aortic segment.

Methods: 22 samples of aorta were evaluated, from patients autopsied, grouped in 11 patients with aneurysm and 11 patients without aneurysm. Macroscopic evaluation of the intensity of atherosclerosis has been described quantitatively in centimeters. Staining were made by Picrosirius for quantification of collagen fibers. The analysis of captured images was performed by software Leica QWin Plus®. For statistical, the data were analyzed with the software GraphPad Prism®.

Results: There was a positive and non significant correlation between the intensity of atherosclerosis and age of the total group (rS = 0.352; p = 0.29).There was a greater intensity of atherosclerosis in relation to age in the group with aortic aneurysm (PA) (U = 26.50; p = 0.03) and higher percentage of collagen fibers (U = 31,950; p < 0.0001)when compared to the NA group. A negative correlation was observed between the percentage of collagen fibers and the intensity of atherosclerosis (rS = −0.109; p = 0.02) (PA).

Conclusions: The intensity of atherosclerosis presented a relation with age, feminine gender, white patients and abdominal aortic segment. The aging process is the cause of atherosclerosis, causing alterations in the arterial walls as an increase of the collagen fibers, thus favoring the appearance of vascular aneurysms.

Copyright
© 2018 Association for Research into Arterial Structure and Physiology. Published by Elsevier B.V. All rights reserved.
Open Access
This is an open access article distributed under the CC BY-NC license.

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<Previous Article In Issue
Next Article In Issue>
Journal
Artery Research
Volume-Issue
22 - C
Pages
43 - 48
Publication Date
2018/05/05
ISSN (Online)
1876-4401
ISSN (Print)
1872-9312
DOI
10.1016/j.artres.2018.04.003How to use a DOI?
Copyright
© 2018 Association for Research into Arterial Structure and Physiology. Published by Elsevier B.V. All rights reserved.
Open Access
This is an open access article distributed under the CC BY-NC license.

Cite this article

risenwbib
TY  - JOUR
AU  - Maria Helena Soares
AU  - Mariana Silva Oliveira
AU  - Aline Cristina Souza da Silva
AU  - Bianca Gonçalves Silva Torquato
AU  - Gabriela Ribeiro Juliano
AU  - Guilherme Ribeiro Juliano
AU  - Márcia Fernandes de Araújo
AU  - Camila Lourencini Cavellani
AU  - Lívia Ferreira Oliveira
AU  - Mara Lúcia Fonseca Ferraz
AU  - Vicente de Paula Antunes Teixeira
PY  - 2018
DA  - 2018/05/05
TI  - Study of atherosclerosis in abdominal aortic aneurysms of autopsied patients
JO  - Artery Research
SP  - 43
EP  - 48
VL  - 22
IS  - C
SN  - 1876-4401
UR  - https://doi.org/10.1016/j.artres.2018.04.003
DO  - 10.1016/j.artres.2018.04.003
ID  - Soares2018
ER  -