Overview: Application of Carbopol 940 in Gel

DOI

10.2991/ahsr.k.210127.018How to use a DOI?

Keywords

Carbopol 940, Gelling agent, Physical properties, Drug release

Abstract

Carbopol is an acrylic polymer. Carbopol is non-toxic and non-irritating so that it is suitable for gel preparations. Carbopol 940 is often used as a gelling agent in gel preparations. Concentration of carbopol 940 as a gelling agent needs to be concerned to obtain a good gel preparation. This study aimed to determine the effect of carbopol 940 concentration on physical properties, drug release and the use in eye drops. The research method used was descriptive method with data collection technique using PICO (Population, Intervention, Compare, Outcame) approach. Based on the Descriptive research results, it was obtained that carbopol 940 had influences on the physical properties of the gel in the form of pH, viscosity, spreadability, adhesion, organoleptic and stability. Carbopol 940 is commonly used in controlled-release drug formulations. In addition, carbopol 940 is also safe to use in eye drops preparations which do not cause irritation in in vivo testing.

Copyright

© 2021, the Authors. Published by Atlantis Press.

Open Access

This is an open access article distributed under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/).

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TY  - CONF
AU  - Fenny Indah Safitri
AU  - Desy Nawangsari
AU  - Dina Febrina
PY  - 2021
DA  - 2021/01/27
TI  - Overview: Application of Carbopol 940 in Gel
BT  - Proceedings of the International Conference on Health and Medical Sciences (AHMS 2020)
PB  - Atlantis Press
SP  - 80
EP  - 84
SN  - 2468-5739
UR  - https://doi.org/10.2991/ahsr.k.210127.018
DO  - 10.2991/ahsr.k.210127.018
ID  - Safitri2021
ER  -