P6.10 ALCOHOL INTAKE IS ASSOCIATED WITH 24-HOUR AORTIC BLOOD PRESSURE IN A YOUNG HEALTHY STUDENT COHORT

James Thomas*; Niamh Chapman; Laura Watkeys; Maria Kearney; Sue King; Eric Stohr; John Cockcroft; Margaret Munnery; Carmel McEniery; Barry McDonnell

doi:10.1016/j.artres.2015.10.294

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Volume 12, Issue C, December 2015, Pages 27 - 27

P6.10 ALCOHOL INTAKE IS ASSOCIATED WITH 24-HOUR AORTIC BLOOD PRESSURE IN A YOUNG HEALTHY STUDENT COHORT

Authors

James Thomas*¹, Niamh Chapman¹, Laura Watkeys¹, Maria Kearney¹, Sue King¹, Eric Stohr¹, John Cockcroft², Margaret Munnery², Carmel McEniery³, Barry McDonnell¹

¹Cardiff School of Health Sciences, Cardiff Metropolitan University, Cardiff, UK

²Wales Heart Research Institute, Cardiff University, Cardiff, UK

³Division of Experimental Medicine and Immunotherapeutics, University of Cambridge, Cambridge, UK

Available Online 23 November 2015.

DOI: 10.1016/j.artres.2015.10.294 How to use a DOI?
Abstract: Objective: Increased brachial (bBP) and aortic blood pressure (aBP) have been linked to increased arterial stiffness and cardiovascular risk in older individuals. Literature suggests that increased alcohol intake is associated with increased BP both acutely and long term in older adults and heavy alcohol drinkers. However, the effects of alcohol intake on 24hour BP and aBP in young healthy adults remains unclear. The purpose of this study was to explore the relationship between weekly alcohol intake and 24-hour BP in a young healthy student cohort.

Methods: Forty-three (11 male, aged 24±5 yrs) healthy students were recruited. Age, height and weight were recorded and weekly alcohol intake reported via self-assessment questionnaire. 24-hour bBP and aBP were measured using the Mobil-O-Graph (IEM, Germany). Aortic BP was calculated using two calibration methods: brachial systolic and diastolic pressures (syst-cal) and mean and diastolic pressures (MAP-cal).

Results: 24-hour aSBP was associated with weekly alcohol consumption, using both calibration methods (r = 0.411, syst-cal; r = 0.54, MAP-cal; both P< 0.05). In addition, 24-hour night-time aSBP (MAP-cal) was associated with weekly alcohol consumption (r = 0.39; P<0.05).

Conclusion: Increased alcohol intake in young healthy students is associated with increased 24 hour and night-time aSBP. These data suggest that excessive alcohol intake at an early age could potentially increase cardiovascular risk via detrimental effects on the vascular system. Larger, longitudinal data are needed to investigate these associations further.
Open Access: This is an open access article distributed under the CC BY-NC license.

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Journal: Artery Research
Volume-Issue: 12 - C
Pages: 27 - 27
Publication Date: 2015/11/23
ISSN (Online): 1876-4401
ISSN (Print): 1872-9312
DOI: 10.1016/j.artres.2015.10.294 How to use a DOI?
Open Access: This is an open access article distributed under the CC BY-NC license.

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ris enw bib

TY  - JOUR
AU  - James Thomas*
AU  - Niamh Chapman
AU  - Laura Watkeys
AU  - Maria Kearney
AU  - Sue King
AU  - Eric Stohr
AU  - John Cockcroft
AU  - Margaret Munnery
AU  - Carmel McEniery
AU  - Barry McDonnell
PY  - 2015
DA  - 2015/11/23
TI  - P6.10 ALCOHOL INTAKE IS ASSOCIATED WITH 24-HOUR AORTIC BLOOD PRESSURE IN A YOUNG HEALTHY STUDENT COHORT
JO  - Artery Research
SP  - 27
EP  - 27
VL  - 12
IS  - C
SN  - 1876-4401
UR  - https://doi.org/10.1016/j.artres.2015.10.294
DO  - 10.1016/j.artres.2015.10.294
ID  - Thomas*2015
ER  -

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