P110 DIFFERENCES IN ARTERIAL STIFFNESS MEASURED BY CARDIO-ANKLE VASCULAR INDEX IN PATIENTS WITH NORMAL AND DECREASED RENAL FUNCTION
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- Abstract
Background: Arterial stiffness (AS) is a highly prognostic risk factor of cardiovascular diseases. The aim of this study was to investigate the relationships between cardio-ankle vascular index (CAVI) and eGFR in patients under the risk of cardiovascular disease.
Methods: This was a retrospective study of Lithuania High cardiovascular risk patients’ database. Demographic, renal function and AS data was gathered. Patients were divided into groups by gender and age by intervals of 5 years. Mean values of CAVI were further investigated according to the patients’ eGFR. ANOVA was used to compare mean values of CAVI.
Results: This study included data of 2070 patients aged from 40 to 65 years. The mean eGFR of the patients was 100.13 ml/min/1.73m2, 58.7% were women. The increase in CAVI was observed with age in overall population, with mean values in different age groups of 6.55±1.28, 7.13±1.84, 7.71±1.92, 7.79±1.95, 7.73±1.98, 8.06±1.79, p < 0.001. Calculation of the mean CAVI in different age and gender groups of eGFR are presented in Table 1. Further comparison of mean values of CAVI did not yield statistically significant results.
eGFR Men Women 40–5 p 45–0 p 50–5 p 50–5 p 55–0 P 60–5 p <60 5,80 0,159 8,58 0,610 7,74 0,150 7,70 0,948 6,34 0,172 7,33 0,068 60–90 6,63 7,80 7,71 7,54 7,73 8,23 >90 7,17 7,67 8,32 7,49 7,78 7,92 Table 1.Mean values of CAVI.
Conclusions: Arterial stiffness increases with age in overall population. There was no statistically significant difference between mean values of CAVI in groups divided by age and gender according to eGFR.
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TY - JOUR AU - Marius Miglinas AU - Alvita Gincaite AU - Laurynas Rimsevicius AU - Ligita Ryliskyte AU - Jolita Badariene AU - Aleksandras Laucevicius PY - 2017 DA - 2017/12/06 TI - P110 DIFFERENCES IN ARTERIAL STIFFNESS MEASURED BY CARDIO-ANKLE VASCULAR INDEX IN PATIENTS WITH NORMAL AND DECREASED RENAL FUNCTION JO - Artery Research SP - 92 EP - 92 VL - 20 IS - C SN - 1876-4401 UR - https://doi.org/10.1016/j.artres.2017.10.141 DO - 10.1016/j.artres.2017.10.141 ID - Miglinas2017 ER -