P137 NUMERICAL ASSESSMENT AND COMPARISON OF PULSE WAVE VELOCITY METHODS PRESUMING TO MEASURE AORTIC STIFFNESS

Hasan Obeid; Gilles Soulat; Elie Mousseaux; Stephane Laurent; Nikolaos Stergiopulos; Pierre Boutouyrie; Patrick Segers

doi:10.1016/j.artres.2017.10.149

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Volume 20, Issue C, December 2017, Pages 94 - 94

P137 NUMERICAL ASSESSMENT AND COMPARISON OF PULSE WAVE VELOCITY METHODS PRESUMING TO MEASURE AORTIC STIFFNESS

Authors

Hasan Obeid¹, Gilles Soulat², Elie Mousseaux², Stephane Laurent², Nikolaos Stergiopulos³, Pierre Boutouyrie², Patrick Segers¹

¹IBiTech-bioMMeda, ELIS Department, iMinds Medical IT, Ghent University, Ghent, Belgium

²Hôpital Européen Georges-Pompidou, Inserm U970, Paris, France

³Laboratory of Hemodynamics and Cardiovascular Technology, Ecole Polytechnique Fédérale de Lausanne EPFL, Switzerland

Available Online 6 December 2017.

DOI: 10.1016/j.artres.2017.10.149 How to use a DOI?
Abstract: Recently several methods have been proposed as tools to measure aortic pulse wave velocity (aPWV). The carotid-femoral pulse wave velocity (cf-PWV), the current clinical gold standard method for the noninvasive assessment of aPWV, uses the carotid–femoral pulse transit time (cf-PTT) to derive cf-PWV. The heart-ankle PWV (ha-PWV), brachial-ankle PWV (ba-PWV) and finger-toe (ft-PWV) are also methods presuming to approximate aPWV based on time delays between physiological signals at two locations (∼heart-ankle PTT, ha-PTT; ∼brachial-ankle PTT, ba-PTT; ∼finger-toe PTT, ft-PTT). To test the validity of these methods, we used a 1D arterial network model (143 segments) including the foot and hand circulation.

The arterial tree dimensions and properties were taken from the literature and completed with CT-scans data. We calculated PTT’s with all the methods above.

The calculated PTT’s were compared with the aortic PTT (aPTT), considered as the absolute reference method in this study. The correlation between methods and aPTT was good and significant, cf-PTT (R² = 0.97; P < 0.001; mean difference 5±2 ms), ha- PTT (R² = 0.96; P < 0.001; 150±23 ms), ba-PTT (R² = 0.96; P < 0.001; 70±13 ms) and ft-PTT (R² = 0.95; P < 0.001; 14±10 ms).

Consequently, good correlation was also observed for the PWV values derived with the tested methods, but absolute values differed because of different path lengths used. In conclusion, our computer model based analyses demonstrate that for PWV methods based on peripheral signals, PTT’s closely correlate with the aPTT, supporting the use of these methods in clinical practice.
Open Access: This is an open access article distributed under the CC BY-NC license.

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Journal: Artery Research
Volume-Issue: 20 - C
Pages: 94 - 94
Publication Date: 2017/12/06
ISSN (Online): 1876-4401
ISSN (Print): 1872-9312
DOI: 10.1016/j.artres.2017.10.149 How to use a DOI?
Open Access: This is an open access article distributed under the CC BY-NC license.

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ris enw bib

TY  - JOUR
AU  - Hasan Obeid
AU  - Gilles Soulat
AU  - Elie Mousseaux
AU  - Stephane Laurent
AU  - Nikolaos Stergiopulos
AU  - Pierre Boutouyrie
AU  - Patrick Segers
PY  - 2017
DA  - 2017/12/06
TI  - P137 NUMERICAL ASSESSMENT AND COMPARISON OF PULSE WAVE VELOCITY METHODS PRESUMING TO MEASURE AORTIC STIFFNESS
JO  - Artery Research
SP  - 94
EP  - 94
VL  - 20
IS  - C
SN  - 1876-4401
UR  - https://doi.org/10.1016/j.artres.2017.10.149
DO  - 10.1016/j.artres.2017.10.149
ID  - Obeid2017
ER  -

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