Artery Research

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Volume 20, Issue C, December 2017, Pages 70 - 71

P60 PSYCHOLOGICAL DETERMINANTS OF TARGET ORGAN DAMAGE IN HYPERTENSIVE PATIENTS: FOCUS ON PULSE WAVE VELOCITY AND DEPRESSION

Authors
Andrea Greco1, Alessandro Maloberti2, 3, Marisa Varrenti2, 3, Ilaria Bassi2, Enrico Piccinelli2, Francesco Panzera2, Stephan Laurent4, 5, 6, Pierre Boutouyrie7, 5, 6, Massimo D’Addario1, Anna Maria Annoni1, Patrizia Steca1, Cristina Giannattasio2, 3
1Department of Psychology, University of Milano-Bicocca, Milan, Italy
2Medicine and Surgery Department, University of Milano-Bicocca, Milan, Italy
3Cardiology IV Unit, “A. De Gasperis” Department, Ospedale Niguarda Ca’ Granda, Milan, Italy
4Université Paris Descartes, Sorbonne Paris Cité, Paris, France
5Inserm U970, Paris, Cardiovascular Research Centre (PARCC), Cardiovascular and epidemiology and Sudden Death Team, Paris, France
6AP-HP, Hopitaux Universitaires Paris Ouest, Department of Pharmacology, Paris, France
7Université Paris Descartes, Sorbonne Paris Cité, Paris, France
Available Online 6 December 2017.
DOI
10.1016/j.artres.2017.10.082How to use a DOI?
Abstract

Objective: Prior studies have suggested that the principal determinants of arterial stiffening are age, BP and others CV risk factors such as dyslipidemia and diabetes. However, scanty data are available on the role of psychological factors on arterial stiffness. The aim of the current cross-sectional study was to evaluate the association between depression, anxiety, perceived stress, Type A personality, and Type D personality and Pulse Wave Velocity (PWV) in a cohort of hypertensive patients, using baseline examination data of the TIPICO project.

Methods: A total of 259 outpatients (ages 18–80 years) followed by the Hypertension Unit of S. Gerardo Hospital (Monza, Italy) affected by essential hypertension were recruited.

Aortic stiffness was evaluated by c-f PWV. Moreover, anamnestic data, clinical BP, and laboratory data were evaluated. Patients were asked to complete a battery of psychological questionnaires under the guidance of a psychologist.

Results: At T0 mean age was 55.9±10.1years, SBP/DBP were 135.6±17.7/82.5±9.1 mmHg and PWV was 8.6±2.1m/s. The multivariate stepwise linear regression analysis showed that age (beta = 0.284, p < 0.001), pulse pressure (beta = 0.369, p < 0.001), dyslipidemia (beta = 0.130, p = 0.012), family history of CV disease (beta = −0.123, p = 0.017), and depression (beta = 0.126, p = 0.014) were significantly and independently associated with PWV.

Conclusion: Among psychological factors, higher levels of depression is related to higher PWV, while anxiety, perceived stress, Type-A personality and Type-D personality are not. Depression assessment and target intervention to reduce it should be recommended in hypertensive patients.

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<Previous Article In Issue
Next Article In Issue>
Journal
Artery Research
Volume-Issue
20 - C
Pages
70 - 71
Publication Date
2017/12/06
ISSN (Online)
1876-4401
ISSN (Print)
1872-9312
DOI
10.1016/j.artres.2017.10.082How to use a DOI?
Open Access
This is an open access article distributed under the CC BY-NC license.

Cite this article

risenwbib
TY  - JOUR
AU  - Andrea Greco
AU  - Alessandro Maloberti
AU  - Marisa Varrenti
AU  - Ilaria Bassi
AU  - Enrico Piccinelli
AU  - Francesco Panzera
AU  - Stephan Laurent
AU  - Pierre Boutouyrie
AU  - Massimo D’Addario
AU  - Anna Maria Annoni
AU  - Patrizia Steca
AU  - Cristina Giannattasio
PY  - 2017
DA  - 2017/12/06
TI  - P60 PSYCHOLOGICAL DETERMINANTS OF TARGET ORGAN DAMAGE IN HYPERTENSIVE PATIENTS: FOCUS ON PULSE WAVE VELOCITY AND DEPRESSION
JO  - Artery Research
SP  - 70
EP  - 71
VL  - 20
IS  - C
SN  - 1876-4401
UR  - https://doi.org/10.1016/j.artres.2017.10.082
DO  - 10.1016/j.artres.2017.10.082
ID  - Greco2017
ER  -