Hypertension: Protective Effects of Physical Exercise on Cognition Function, Arterial Function and Brain Health
PRÓ-SQUALUS-PROJETO CARCHARIAS (Organização para a Pesquisa e a Conservação de Esqualos no Brasil) - Health and Quality of Life Department, Torres, Rio Grande do Sul, Brazil
Grupo de Pesquisa em Ciência e Saúde Coletiva (GPCSC/FVA), Araranguá, Santa Catarina, Brazil
- DOI
- 10.2991/artres.k.191203.003How to use a DOI?
- Keywords
- Hypertension; cognition; exercise; vascular health; rehabilitation
- Abstract
Systemic Arterial Hypertension (SAH) is a chronic condition that requires clinical treatment and is associated with increased risk of cognitive impairment and dementia. Therefore, strategies with fewer side effects and less invasive procedures are required. Evidence supports that Physical Exercise (PE) has antihypertensive effects and has proven to be an efficient and complementary tool for managing hypertension, reducing cardiovascular disease risk factors, and improving cerebral perfusion in the majority of healthy populations. Much of this cardiovascular-protective effect of PE is probably due to pluripotent effects on the vasculature, including regulation of vascular tone, energy metabolism, microvascular recruitment, and endothelial function (reducing oxidative stress and preserving NO availability). These factors are speculated to work synergistically, thereby reducing systolic and diastolic blood pressure and are directly related to improved cerebrovascular function. However, few studies have specifically examined the potential positive effects of PE on the brain in hypertensive individuals. In this brief review, we discuss the potential effect of different PE modalities (aerobic, resistance, and combined) that may act as an effective preventive or therapeutic strategy for reducing blood pressure in hypertensives and, consequently, mitigate the association between hypertension, cognitive impairment and risk of dementia.
- Copyright
- © 2019 Association for Research into Arterial Structure and Physiology. Publishing services by Atlantis Press International B.V.
- Open Access
- This is an open access article distributed under the CC BY-NC 4.0 license (http://creativecommons.org/licenses/by-nc/4.0/).
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TY - JOUR AU - Marinei Lopes Pedralli AU - Eduardo Barbosa AU - Pedro Guimarães Cunha PY - 2019 DA - 2019/12/17 TI - Hypertension: Protective Effects of Physical Exercise on Cognition Function, Arterial Function and Brain Health JO - Artery Research SP - 81 EP - 86 VL - 25 IS - 3-4 SN - 1876-4401 UR - https://doi.org/10.2991/artres.k.191203.003 DO - 10.2991/artres.k.191203.003 ID - Pedralli2019 ER -