Artery Research

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Volume 5, Issue 3, September 2011, Pages 81 - 90

Atherosclerotic vascular disorders in HIV infected patients

Authors
John Palios, Ignatios Ikonomidis*, John Lekakis, Maria Anastasiou-Nana
2nd Department of Cardiology, Attikon University Hospital, University of Athens, Medical School, Greece
*Corresponding author. Attikon University Hospital, Perikleous 19, 1434 N Chalkidona, Athens, Greece, Fax: +30 210 5832192. E-mail address: ignoik@otenet.gr (I. Ikonomidis).
Corresponding Author
Ignatios Ikonomidis
Received 11 March 2010, Revised 2 April 2011, Accepted 14 April 2011, Available Online 29 July 2011.
DOI
10.1016/j.artres.2011.04.001How to use a DOI?
Keywords
HIV; Atherosclerosis; HAART; Arterial stiffness; Carotid; Microcirculation
Abstract

Individuals infected with human immunodeficiency virus (HIV) frequently demonstrate a metabolic syndrome associated with atherosclerosis and cardiovascular disease. Extensive functional and structural arterial wall changes have been observed in these individuals. It is documented that these vascular changes are closely related to highly active antiretroviral therapy (HAART) -induced disorders of metabolic parameters such as serum glucose, cholesterol, triglycerides and arterial blood pressure. In addition, characteristics of the HIV infection itself such as immunodeficiency, viral load, duration of the disease, appear to influence the pathogenesis of these vascular changes. Intensive treatment of vascular dysfunction might be helpful in preventing or retarding the atherosclerotic process in HIV patients.

Copyright
© 2011 Association for Research into Arterial Structure and Physiology. Published by Elsevier B.V. All rights reserved.
Open Access
This is an open access article distributed under the CC BY-NC license.

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Next Article In Issue>
Journal
Artery Research
Volume-Issue
5 - 3
Pages
81 - 90
Publication Date
2011/07/29
ISSN (Online)
1876-4401
ISSN (Print)
1872-9312
DOI
10.1016/j.artres.2011.04.001How to use a DOI?
Copyright
© 2011 Association for Research into Arterial Structure and Physiology. Published by Elsevier B.V. All rights reserved.
Open Access
This is an open access article distributed under the CC BY-NC license.

Cite this article

risenwbib
TY  - JOUR
AU  - John Palios
AU  - Ignatios Ikonomidis
AU  - John Lekakis
AU  - Maria Anastasiou-Nana
PY  - 2011
DA  - 2011/07/29
TI  - Atherosclerotic vascular disorders in HIV infected patients
JO  - Artery Research
SP  - 81
EP  - 90
VL  - 5
IS  - 3
SN  - 1876-4401
UR  - https://doi.org/10.1016/j.artres.2011.04.001
DO  - 10.1016/j.artres.2011.04.001
ID  - Palios2011
ER  -