Artery Research

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Volume 19, Issue C, September 2017, Pages 38 - 41

Assessment of the relationship between serum uric acid level and atherosclerosis burden in patients undergoing coronary angiography in Ekbatan (Farshchian) hospital, Hamadan 2015

Authors
Mohammadreza Bayanatia, Soudabeh Keshtkarb, *, Maryam Farhadianc, Fatemeh Ashtaranid
aDepartment of Cardiology, School of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran
bClinical Research Development Unit of Farshchian Heart Center, Department of Cardiology, School of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran
cModeling of Noncommunicable Disease Research Center, Department of Biostatistics, School of Public Health, Hamadan University of Medical Sciences, Hamadan, Iran
dClinical Research Development Unit of Farshchian Hospital, Hamadan University of Medical Sciences, Hamadan, Iran
*Corresponding author. Fax: +98 81 38381686. E-mail address: soudabehkeshtkar@yahoo.com (S. Keshtkar).
Corresponding Author
Soudabeh Keshtkar
Received 14 March 2017, Revised 10 June 2017, Accepted 13 June 2017, Available Online 6 July 2017.
DOI
10.1016/j.artres.2017.06.002How to use a DOI?
Keywords
Atherosclerosis; Uric acid; Coronary artery; Angiography; Iran
Abstract

Background: Nowadays, cardiac disease is the most widespread reason of death in most countries such as Iran. Some studies have correlated serum uric acid level with risk of death in the patients of acute coronary syndrome. The study aimed to determine if there is any correlation between serum uric level and atherosclerosis burden.

Material and methods: In this cross-sectional study, all the patients underwent coronary angiography in Hamadan’s Ekbatan Hospital in 2015 and were studied in terms of demographic, serum lipid profile, blood glucose and uric acid. Data were obtained from patients’ medical records, registered in data sheet and analyzed by spss16 statistical software.

Results: 140 patients participated in this study of whom 60% were male and 40% female with age mean of 62.92 ± 11.21 years old. Blood uric acid’s mean was 6.39 ± 2.16 mg/dl and based on coronary artery involvement range was single vessel disease (6.17 ± 1.91), two vessel disease (6.56 ± 2.17), three vessel disease (6.32 ± 2.01), mild or minimal or patent (6.78 ± 3.16) and in ectatic or slow flow (7.30 ± 0.86) mg/dl, respectively. According to the results of Kruskal–Wallis test, no significant relation was observed between uric acid level and the range of coronary artery involvement (P = 0.60). But, the mean of serum uric acid level in severe Ischemic heart disease was significantly more than acute coronary syndrome (P = 0.04).

Conclusion: Blood uric acid is not a dependent predictive risk factor of atherosclerosis but through effects on other risk factors it may increase the risk of heart disease.

Copyright
© 2017 Association for Research into Arterial Structure and Physiology. Published by Elsevier B.V. All rights reserved.
Open Access
This is an open access article distributed under the CC BY-NC license.

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<Previous Article In Issue
Next Article In Issue>
Journal
Artery Research
Volume-Issue
19 - C
Pages
38 - 41
Publication Date
2017/07/06
ISSN (Online)
1876-4401
ISSN (Print)
1872-9312
DOI
10.1016/j.artres.2017.06.002How to use a DOI?
Copyright
© 2017 Association for Research into Arterial Structure and Physiology. Published by Elsevier B.V. All rights reserved.
Open Access
This is an open access article distributed under the CC BY-NC license.

Cite this article

risenwbib
TY  - JOUR
AU  - Mohammadreza Bayanati
AU  - Soudabeh Keshtkar
AU  - Maryam Farhadian
AU  - Fatemeh Ashtarani
PY  - 2017
DA  - 2017/07/06
TI  - Assessment of the relationship between serum uric acid level and atherosclerosis burden in patients undergoing coronary angiography in Ekbatan (Farshchian) hospital, Hamadan 2015
JO  - Artery Research
SP  - 38
EP  - 41
VL  - 19
IS  - C
SN  - 1876-4401
UR  - https://doi.org/10.1016/j.artres.2017.06.002
DO  - 10.1016/j.artres.2017.06.002
ID  - Bayanati2017
ER  -