Predictors of Quality of Life in Transfusion-dependent Thalassemia Patients Based on the PRECEDE Model: A Structural Equation Modeling Approach

Mina Maheri; Alireza Rohban; Roya Sadeghi; Hamid Joveini

doi:10.2991/jegh.k.191001.001

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Volume 10, Issue 2, June 2020, Pages 157 - 163

Predictors of Quality of Life in Transfusion-dependent Thalassemia Patients Based on the PRECEDE Model: A Structural Equation Modeling Approach

Authors

Mina Maheri¹, Alireza Rohban², Roya Sadeghi³^{, *}, Hamid Joveini⁴

¹Department of Public Health, School of Health, Reproductive Health Research Center, Urmia University of Medical Sciences, Urmia, Iran

²School of Rehabilitation Sciences, Iran University of Medical Sciences, Tehran, Iran

³Department of Health Education and Promotion, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran

⁴Department of Health Education, School of Health, Sabzevar University of Medical Sciences, Sabzevar, Iran

^*Corresponding author. Email: sadeghir@tums.ac.ir

Corresponding Author

Roya Sadeghi

Received 4 July 2019, Accepted 18 September 2019, Available Online 16 October 2019.

DOI: 10.2991/jegh.k.191001.001 How to use a DOI?
Keywords: Quality of life; transfusion-dependent thalassemia; PRECEDE model
Abstract: This study aimed to determine the predictors of Quality of Life (QoL) in Transfusion-Dependent Thalassemia (TDT) patients based on PRECEDE (Predisposing, Reinforcing and Enabling Constructs in Educational Diagnosis and Evaluation) model. This cross-sectional analytical study was performed on 389 TDT patients who were under treatment in four thalassemia centers in Tehran, Iran. Data gathering instrument consisted of three parts: socioeconomic and demographic information, the Persian version of the six standardized questionnaires for measuring some of the potential predictive factors of QoL in TDT patients based on the PRECEDE model constructs, and a researcher-made questionnaire to assess knowledge of patients about health- and QoL-promoting behaviors and enabling factors involved in health- and QoL-promoting behaviors. Using AMOS 23.0, the structural equation modeling with maximum likelihood estimation was conducted to test the proposed hypotheses. Associations of QoL with all of the PRECEDE model constructs, including anxiety–depression, self-efficacy, perceived barriers, knowledge, enabling factors, and reinforcing factors were significant (all p < 0.001). Anxiety–depression and perceived barriers were the significant negative predictors of QoL in TDT patients, whereas health-promoting lifestyle was the significant positive predictor of QoL in TDT patients. The final conceptual model of the study was adequately fit and can be applied as a framework for future educational-supportive programs aimed at improving the QoL in TDT patients.
Open Access: This is an open access article distributed under the CC BY-NC 4.0 license (http://creativecommons.org/licenses/by-nc/4.0/).

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Journal: Journal of Epidemiology and Global Health
Volume-Issue: 10 - 2
Pages: 157 - 163
Publication Date: 2019/10/16
ISSN (Online): 2210-6014
ISSN (Print): 2210-6006
DOI: 10.2991/jegh.k.191001.001 How to use a DOI?
Open Access: This is an open access article distributed under the CC BY-NC 4.0 license (http://creativecommons.org/licenses/by-nc/4.0/).

Cite this article

ris enw bib

TY  - JOUR
AU  - Mina Maheri
AU  - Alireza Rohban
AU  - Roya Sadeghi
AU  - Hamid Joveini
PY  - 2019
DA  - 2019/10/16
TI  - Predictors of Quality of Life in Transfusion-dependent Thalassemia Patients Based on the PRECEDE Model: A Structural Equation Modeling Approach
JO  - Journal of Epidemiology and Global Health
SP  - 157
EP  - 163
VL  - 10
IS  - 2
SN  - 2210-6014
UR  - https://doi.org/10.2991/jegh.k.191001.001
DO  - 10.2991/jegh.k.191001.001
ID  - Maheri2019
ER  -

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